M13 Bacteriophage-Based Bio-nano Systems for Bioapplication
- Title
- M13 Bacteriophage-Based Bio-nano Systems for Bioapplication
- Author
- 이주헌
- Keywords
- M13 bacteriophage; Biomimetic; Surface engineering; Self-assembly; Biosensor
- Issue Date
- 2022-07
- Publisher
- KOREAN BIOCHIP SOCIETY-KBCS
- Citation
- BIOCHIP JOURNAL, v. 16.0, NO. 3, Page. 227-245
- Abstract
- M13 bacteriophage is a promising biomolecule with unique biochemical and structural traits (e.g., high aspect ratio, 2700 copies of identical coat proteins covering the phage surface) that can also be programmable, making it a versatile material for bio-nano and biomimetic applications. Although M13 bacteriophage is mostly known as a carrier in the phage display screening process, pioneers have used the phage's properties to develop the virus into a bionanomaterial that can be used for various applications. This study reviews M13 bacteriophage-based bio-nano systems derived from the structural and biochemical properties of M13 bacteriophage for both bio-nano and material science applications. Two major approaches regarding the fabrication of the bio-nano systems are introduced: surface engineering of individual M13 bacteriophage into single bio-nano templates and self-assembly of M13 bacteriophages into bio-nano matrices. Various genetic engineering and chemical engineering methods are reported for the surface engineering of M13 bacteriophage, which enables the bionanomaterial to have a wide range of functionalities. The bio-nano and material science applications of the self-assembled bio-nano matrices are also examined in this study. These complex engineered M13 bacteriophage-based matrices are capable of guiding a new generation of bionanomaterials for bio-nano and material science applications.
- URI
- https://link.springer.com/article/10.1007/s13206-022-00069-whttps://repository.hanyang.ac.kr/handle/20.500.11754/177629
- ISSN
- 1976-0280;2092-7843
- DOI
- 10.1007/s13206-022-00069-w
- Appears in Collections:
- COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > BIONANO ENGINEERING(생명나노공학과) > Articles
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