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Progression of Parapapillary Choroidal Microvascular Dropout After Disc Hemorrhage in Glaucoma Patients: 2 Case Reports

Title
Progression of Parapapillary Choroidal Microvascular Dropout After Disc Hemorrhage in Glaucoma Patients: 2 Case Reports
Author
이원준
Keywords
glaucoma; optical coherence tomography angiography; microvasculature dropout; disc hemorrhage
Issue Date
2021-01
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Citation
JOURNAL OF GLAUCOMA, v. 30, NO 1, Page. E8-E12
Abstract
Purpose: Microvasculature dropout (MvD) is a novel finding seen in optical coherence tomography angiography (OCTA), which is characterized by a localized dehiscence of the choriocapillaris in the parapapillary atrophy area. Disc hemorrhage (DH) is an important factor often associated with the development and especially progression of glaucoma. Here, we present 2 cases of MvD progression with DH. Methods and Results: Case 1: A 62-year-old female patient with normal tension glaucoma in both her eyes had recurrent DH at the inferior area of her right eye. A new DH was observed in the inferotemporal area of the right eye with MvD progression on OCTA in the same direction three months from the baseline. Case 2: A 57-year-old female patient with bilateral steroid-induced secondary glaucoma also had recurrent DH in her right eye. Four months from the baseline, DH occurred in the superotemporal and inferotemporal area of the right eye, and MvD was detected on OCTA in the superotemporal corresponding direction. After 19 months from the baseline, OCTA was repeated. The DH had resolved, but the superotemporal MvD persisted. Conclusions: The 2 cases presented here are the first to report on the relationship between MvD progression and DH. MvD as visualized in OCTA imaging looks to be of clinical importance, and hopefully future studies will reveal the actual connection between MvD, DH, and glaucoma progression.
URI
https://journals.lww.com/glaucomajournal/Fulltext/2021/01000/Progression_of_Parapapillary_Choroidal.22.aspxhttps://repository.hanyang.ac.kr/handle/20.500.11754/175243
ISSN
1057-0829; 1536-481X
DOI
10.1097/IJG.0000000000001688
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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