Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이원준 | - |
dc.date.accessioned | 2022-10-11T04:28:06Z | - |
dc.date.available | 2022-10-11T04:28:06Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.citation | SCIENTIFIC REPORTS, v. 11, NO 1, article no. 1264 | en_US |
dc.identifier.issn | 2045-2322 | en_US |
dc.identifier.uri | https://www.nature.com/articles/s41598-020-80321-1 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/175175 | - |
dc.description.abstract | The present study aimed to identify vibroacoustic properties associated with intraocular pressure (IOP) changes and to suggest a new way to measure the IOP based on these properties. Ten ex vivo porcine eyeballs were used in this study. Each eyeball was fixated in a central hole of a Styrofoam block, and vibration applied to the Styrofoam block was transmitted to the eyeball. An accelerometer directly attached to the eyeball measured the vibration response. Excitations and measurements were performed for 1 s, and the excitation magnitude was varied for the same signal in repeat measurements. A 30-gauge needle was inserted into the anterior chamber of the eyeball to inject a balanced salt solution, and the height of the bottle was adjusted to adjust the IOP. A tonometer was used under identical conditions to measure the IOP five times, and the mean value was determined for further analyses. The measurements showed that the parameters resonance frequency and change in the magnitude of the vibration response (CMVR) increased with rising IOP values. The CMVR was highly correlated with the IOP (p-value < 0.0001). A linear mixed effects model (LMM) was used as a statistical analysis method. We confirmed that vibroacoustic properties of the eyeball are correlated with IOP changes. It is expected that the CMVR will serve as a new parameter for IOP measurements. Thus, in the future, continuous IOP measurements would be easily performed using the CMVR. | en_US |
dc.description.sponsorship | This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) and funded by the Korean government (MSIT) [Grant number 2019M3E5D1A01069363]. | en_US |
dc.language.iso | en | en_US |
dc.publisher | NATURE RESEARCH | en_US |
dc.title | A pilot study for intraocular pressure measurements based on vibroacoustic parameters | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.1038/s41598-020-80321-1 | en_US |
dc.relation.page | 1-10 | - |
dc.relation.journal | SCIENTIFIC REPORTS | - |
dc.contributor.googleauthor | Kim, Deukha | - |
dc.contributor.googleauthor | Chung, Youngbeen | - |
dc.contributor.googleauthor | Yeon, Yeji | - |
dc.contributor.googleauthor | Cho, Hyunsoo | - |
dc.contributor.googleauthor | Lim, Han Woong | - |
dc.contributor.googleauthor | Park, Junhong | - |
dc.contributor.googleauthor | Lee, Won June | - |
dc.relation.code | 2021002638 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | wonjunelee | - |
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