111 0

Comparison of core‑needle biopsy and repeat fine‑needle aspiration for thyroid nodules with inconclusive initial cytology

Title
Comparison of core‑needle biopsy and repeat fine‑needle aspiration for thyroid nodules with inconclusive initial cytology
Author
정민성
Keywords
Core-needle biopsy; Fine-needle aspiration; Thyroid nodule; Thyroid cancer
Issue Date
2020-11
Publisher
SPRINGER
Citation
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, v. 278, no. 8, page. 3019-3025
Abstract
Purpose: We aimed to compare the efcacy of ultrasound-guided core-needle biopsy (CNB) with repeat fne-needle aspiration (rFNA) cytology in thyroid nodules with inconclusive results in initial fne-needle aspiration cytology. Methods: We studied 402 patients who required a repeat biopsy of thyroid nodules using ultrasound-guided CNB (n=192) or rFNA (n=210) because of inconclusive results in initial FNA, corresponding to categories I, III, and IV of the Bethesda System for Reporting Thyroid Cytopathology. If repeat biopsy results were benign (category II), suspicious malignancy (category V), or malignancy (category VI), they were defned as “diagnostic results”. The diagnostic yield and performances of repeat biopsy were analyzed and compared between the rFNA and CNB groups. Results: The diagnostic results were obtained signifcantly higher in the CNB group than in the rFNA group (72.4% vs. 52.4%; P<0.001). In the subgroup analysis, the diagnostic results were signifcantly higher in the CNB group than in the rFNA group for patients of categories I and III (P<0.001 in both) in initial FNA. However, in patients with category IV nodules, there were no signifcant diferences in diagnostic results between the two groups (P=0.46). Conclusion: Compared to rFNA, ultrasound-guided CNB is useful and efective as a repeat biopsy option for thyroid nodules with non-diagnostic results (category I) and atypia of undetermined signifcance (AUS) or follicular lesion of undetermined signifcance (FLUS) (category III) in initial FNA.
URI
https://link.springer.com/article/10.1007/s00405-020-06473-yhttps://repository.hanyang.ac.kr/handle/20.500.11754/172734
ISSN
0937-4477; 1434-4726
DOI
10.1007/s00405-020-06473-y
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE