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Coating of a Sand-Blasted and Acid-Etched Implant Surface with a pH-Buffering Agent after Vacuum-UV Photofunctionalization

Title
Coating of a Sand-Blasted and Acid-Etched Implant Surface with a pH-Buffering Agent after Vacuum-UV Photofunctionalization
Author
황경균
Keywords
blood clotting; dental implants; hydrophilicity; titanium; ultraviolet rays
Issue Date
2020-10
Publisher
MDPI
Citation
COATINGS, v. 10, no. 11, article no. 1040
Abstract
Ultraviolet (UV) photofunctionalization can reset the biological aging of titanium after the preparation and storage of dental implants by transforming hydrophobic titanium surfaces into superhydrophilic surfaces. Blood clot formation around the implant can initialize and promote the healing process at the bone-implant interface. The aim of this study is to evaluate and compare the capabilities of surface wettability and blood clotting of implants with a conventional sand-blasted and acid-etched surface (SA), a sand-blasted and acid-etched surface with vacuum-UV treatment (SA + VUV), and a sand-blasted and acid-etched surface coated with a pH-buffering agent after vacuum-UV treatment (SA + VUV + BS). Static and dynamic tests for surface wettability and blood clotting were performed in vitro for SA + VUV and SA + VUV + BS (n = 5), while hemostasis resulting from blood clotting was evaluated in vivo for SA, SA +VUV, and SA + VUV + BS (n = 4). A Kruskal-Wallis test showed statistically significant differences (p ˂ 0.05) in all tests, with the exception of in vitro test of static blood clotting. VUV treatment is therefore effective at making an SA surface superhydrophilic as an alternative to routine UV-C radiation. The addition of a pH-buffering agent to SA + VUV also improved surface wettability and blood clotting, which are crucial for successful osseointegration.
URI
https://www.mdpi.com/2079-6412/10/11/1040https://repository.hanyang.ac.kr/handle/20.500.11754/171128
ISSN
2079-6412
DOI
10.3390/coatings10111040
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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