Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 채필석 | - |
dc.date.accessioned | 2022-05-23T06:51:17Z | - |
dc.date.available | 2022-05-23T06:51:17Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.citation | DYES AND PIGMENTS, v. 198, Page. 110025-110025 | en_US |
dc.identifier.issn | 0143-7208 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0143720821008913 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/171063 | - |
dc.description.abstract | Mercury ions are an industrial and environmental toxin that need to be monitored and regulated in aqueous samples. We prepared six probes (1-6) using a naphthoquinolinedione ring as a fluorophore platform that contains different substituents on the quinolone ring. All probes showed abilities to selectively bind Hg2+, but their sensitivity to the detection of this metal ion significantly varied depending on the substituent pattern. Among these probes, probe 5 with Br and CN substituents on the quinolone ring was most effective for the sensitive detection of Hg2+ in aqueous solutions. This probe showed a naked-eye color change from yellow to purple upon binding to Hg2+. A ratio-metric method using UV-visible absorption data gave a limit of detection (LOD) of 20 nM, while the fluorescence-based result yielded an LOD of 0.047 pM. When bio-samples such as human urine and serum were used as media, the fluorescence-based LOD of this probe for Hg2+ detection increased to 50 nM. Probe 5 was also effective at detecting methylmercury, an organic mercury species, dissolved in drainage water or urine. Based on the results of DLS, FE-SEM, and DFT calculations, the probe appeared to form large aggregates and undergo photo-induced electron transfer (PET) upon Hg2+ binding, both of which are responsible for the probe fluorescence quenching. Probe 5 also showed the ability to sense Hg2+ within three different types of human cells: Brain cells (U87MG), Hela cells and skin cancer cells (SK-MEL28). Furthermore, this probe holds significant potential for on-site applications since various solid supports such as silica gel, filter papers and TLC plates were effectively used for sensitive and selective Hg2+ sensing, following probe coating/adsorption. | en_US |
dc.description.sponsorship | This work was supported by the National Research Foundation of Korea (NRF) (2018R1A6A1A03024231 to P.S.C.). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER SCI LTD | en_US |
dc.subject | Naphthoquinolinedione | en_US |
dc.subject | Hg2+/methylmercury detection | en_US |
dc.subject | Fluorescence quenching | en_US |
dc.subject | Naked eye detection | en_US |
dc.subject | Bio-detection | en_US |
dc.title | Chromofluorogenic naphthoquinolinedione-based probes for sensitive detection and removal of Hg2+ in aqueous solutions | en_US |
dc.type | Article | en_US |
dc.relation.volume | 198 | - |
dc.identifier.doi | 10.1016/j.dyepig.2021.110025 | - |
dc.relation.page | 110025-110025 | - |
dc.relation.journal | DYES AND PIGMENTS | - |
dc.contributor.googleauthor | Kumar, Ashwani | - |
dc.contributor.googleauthor | Hur, Won | - |
dc.contributor.googleauthor | Seong, Gi Hun | - |
dc.contributor.googleauthor | Kumar, Subodh | - |
dc.contributor.googleauthor | Chae, Pil Seok | - |
dc.relation.code | 2022041765 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF BIONANO ENGINEERING | - |
dc.identifier.pid | pchae | - |
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