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dc.contributor.author윤영은-
dc.date.accessioned2022-04-20T00:25:04Z-
dc.date.available2022-04-20T00:25:04Z-
dc.date.issued2020-08-
dc.identifier.citationBIOMED RESEARCH INTERNATIONAL, v. 2020, Page. 1-10en_US
dc.identifier.issn2314-6133-
dc.identifier.issn2314-6141-
dc.identifier.urihttps://www.hindawi.com/journals/bmri/2020/4605683/-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/170129-
dc.description.abstractIntroduction. We investigated which benign prostatic hyperplasia-related lower urinary parameters are related to upper urinary tract obstruction and whether transurethral prostatectomy could improve upper urinary tract obstruction. Materials and Methods. Patients with prostate size over 30 g and urodynamically proven bladder outlet obstruction were enrolled in this prospective observational study. Bladder wall thickness and prostate size were measured by ultrasonography. A urodynamic study with laboratory tests including serum creatinine, prostate-specific antigen, and urinalysis was performed. Finally, a diuretic scintigraphy using mercaptoacetyltriglycine was performed. Tests except the urodynamic evaluation were repeated after transurethral prostatectomy. Results. In total, 24 patients were enrolled, and 19 patients completed the present study. The mean values of age (yrs), prostate size (mL), bladder thickness (mm), bladder compliance (Delta mL/Delta pr), and the bladder outlet obstruction index were 68.42 +/- 8.25, 72.29 +/- 32.78, 4.42 +/- 1.14, 50.17 +/- 32.15, and 82.11 +/- 34.68, respectively. The mean T-1/2 (min) was 17.51 +/- 16.34 on the left side and 15.30 +/- 11.96 on the right side. Statistical analysis showed that bladder compliance and bladder thickness were preoperatively related to upper urinary tract obstruction (p=0.001 and p=0.007, respectively). Diuretic mercaptoacetyltriglycine scan in 19 patients showed improvement 6 months after prostate surgery. Clinically significant proteinuria was associated with upper urinary tract obstruction, and proteinuria was also improved after prostate surgery. Conclusion. Storage-phase bladder dysfunction could be a reliable urodynamic factor for the indication of upper urinary tract obstruction in patients with benign prostatic hyperplasia, and upper urinary tract obstruction with subsequent kidney damage could be improved by surgical decompression of benign prostatic obstruction.en_US
dc.description.sponsorshipThe authors are particularly grateful to all patients who participated in the whole course of this study. This work was supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) (No. 2019R1C1C1008339).en_US
dc.language.isoenen_US
dc.publisherHINDAWI LTDen_US
dc.subjectCHRONIC KIDNEY-DISEASEen_US
dc.subjectBLADDER OUTLET OBSTRUCTIONen_US
dc.subjectTRANSURETHRAL RESECTIONen_US
dc.subjectSYMPTOM SCOREen_US
dc.subjectHYPERPLASIAen_US
dc.subjectMENen_US
dc.subjectCONTRACTILITYen_US
dc.subjectPARAMETERSen_US
dc.subjectRETENTIONen_US
dc.subjectDEFINEen_US
dc.titleFunctional Evaluation of Upper Urinary Tract with Diuretic Mercaptoacetyltriglycine Renal Scans in Patients with Benign Prostatic Obstruction before and after Surgical Intervention: A Pilot Studyen_US
dc.typeArticleen_US
dc.relation.volume2020-
dc.identifier.doi10.1155/2020/4605683-
dc.relation.page1-10-
dc.relation.journalBIOMED RESEARCH INTERNATIONAL-
dc.contributor.googleauthorCho, Sung Yong-
dc.contributor.googleauthorKo, Kyungtae-
dc.contributor.googleauthorKoo, Kyo Chul-
dc.contributor.googleauthorKim, Hyung Joon-
dc.contributor.googleauthorBang, Woo Jin-
dc.contributor.googleauthorChoo, Min Soo-
dc.contributor.googleauthorLee, Sang Hyub-
dc.contributor.googleauthorYoon, Young Eun-
dc.contributor.googleauthorJung, Wonho-
dc.contributor.googleauthorChoi, Jae Young-
dc.relation.code2020051748-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidurologistyoon-
dc.identifier.researcherIDABG-4983-2020-
dc.identifier.orcidhttps://orcid.org/0000-0001-8059-6649-


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