208 0

Total Synthesis of Arucadiol and 1-Oxomiltirone with Gold and Copper-catalyzed Cyclization and The Synthetic Approach of [6,6,6]-Tricyclic Abietane Analogues

Title
Total Synthesis of Arucadiol and 1-Oxomiltirone with Gold and Copper-catalyzed Cyclization and The Synthetic Approach of [6,6,6]-Tricyclic Abietane Analogues
Other Titles
금과 구리 촉매를 이용한 고리화 반응으로 Arucadiol과 1-Oxomiltirone의 전합성연구와 [6,6,6]-Tricyclic Abietane Analogues 합성 연구
Author
성채현
Alternative Author(s)
성채현
Advisor(s)
오창호
Issue Date
2021. 8
Publisher
한양대학교
Degree
Master
Abstract
Part 1. Total Synthesis of Arucadiol and 1-Oxomiltirone with Gold and Copper-catalyzed Cyclization Natural products with many important biological activities are mostly composed of multiple ring compounds. In particular, abietanes are natural product, triple ring compounds, that has been studied and have many biological activities like excellent antibacterial activity. Among them, we effectively synthesized arucadiol and 1-oxomiltirone, which have excellent antibacterial and anticancer properties, through a cyclization reaction with gold and copper catalysts. Part 2. The Synthetic Approach of [6,6,6]-Tricyclic Abietane Analogue Cyclization in mamy complicated structures using transition-metal catalysts have been studied for long time. The reaction using transition-metals is considered important synthetic pathways because is able to synthesize selective and effectively. We synthesized several abietane analogues, [6,6,6]-tricyclic compounds, using gold and copper catalysts.
URI
http://hanyang.dcollection.net/common/orgView/200000490319https://repository.hanyang.ac.kr/handle/20.500.11754/163729
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > CHEMISTRY(화학과) > Theses (Master)
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE