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A Facile Synthesis of Cis-9-[4-(1,2-Dihydroxyethyl)-cyclopent-2-enyl]guanine and Its Derivative

Title
A Facile Synthesis of Cis-9-[4-(1,2-Dihydroxyethyl)-cyclopent-2-enyl]guanine and Its Derivative
Author
이학준
Issue Date
2000-10
Publisher
Marcel Decker
Citation
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v. 19, no. 7, page. 1111-1122
Abstract
The synthesis of carbocyclic nucleosides, cis-9-[4-(1,2-dihydroxyethyl)-cyclopent-2-enyl]guanine (3) and cis-2-amino-6-cyclopropylamino-9-[4-(1,2-dihydroxyethyl)-cyclopent-2-enyl]guanine (4), was achieved from cyclopentadiene (5) in five and six steps, respectively. This route involves a hetero Diels-Alder reaction and a Pd(0)-catalyzed coupling reaction.
URI
https://www.tandfonline.com/doi/abs/10.1080/15257770008035034https://repository.hanyang.ac.kr/handle/20.500.11754/162615
DOI
10.1080/15257770008035034
Appears in Collections:
COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E](과학기술융합대학) > CHEMICAL AND MOLECULAR ENGINEERING(화학분자공학과) > Articles
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