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dc.contributor.author임한웅-
dc.date.accessioned2021-05-14T07:36:09Z-
dc.date.available2021-05-14T07:36:09Z-
dc.date.issued2020-03-
dc.identifier.citationJOURNAL OF CLINICAL MEDICINE, v. 9, no. 3, article no. 883en_US
dc.identifier.issn2077-0383-
dc.identifier.urihttps://www.mdpi.com/2077-0383/9/3/883-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/162059-
dc.description.abstractIn this cross-sectional study, we examined age-related changes in the retinal vessels of 100 healthy participants, aged from 5 to 80 years, and divided into four groups (G1, under 20 years of age; G2, from 20 to 39 years of age; G3, from 40 to 59 years of age; G4, age 60 years or older). All subjects underwent swept-source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). The vascular density (VD) of the superficial (SCP) and deep capillary plexus (DCP), and choriocapillaris (CCP) were measured using OCTA. The vascular density of each capillary layer, foveal avascular zone (FAZ) area, ganglion cell-inner plexiform layer (GC-IPL) thickness, retinal thickness (RT), and choroidal thickness (CT) were compared between age groups. Most OCT variables were correlated with OCTA variables. The FAZ area; VD of the SCP, DCP, and CCP; GC-IPL thickness; RT; and CT showed significant difference (p < 0.001) between G1 + G2 and G3 + G4, except for central GC-IPL thickness (p = 0.14) and central RT (p = 0.25). Density of the retinal capillary vasculature reduced and FAZ area increased after age 40, which represents the onset of middle age.en_US
dc.description.sponsorshipThis work was supported by the National Research Foundation of Korea (NRF) grants funded by the Korea government (the Ministry of Science and ICT, NRF-2019R1A2C4070638 to HWL, the Ministry of Education, NRF-2017R1D1A1B03030905 to YUS, and NRF-2017R1D1A1B03031934 to HC).en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectoptical coherence tomography angiographyen_US
dc.subjectageen_US
dc.subjectretinal capillary vascular densityen_US
dc.subjectchoriocapillaris vascular densityen_US
dc.subjectswept-source optical coherence tomographyen_US
dc.titleChanges in the Retinal Microvasculature Measured Using Optical Coherence Tomography Angiography According to Ageen_US
dc.typeArticleen_US
dc.relation.no3-
dc.relation.volume9-
dc.identifier.doi10.3390/jcm9030883-
dc.relation.page1-12-
dc.relation.journalJOURNAL OF CLINICAL MEDICINE-
dc.contributor.googleauthorPark, Seung Hun-
dc.contributor.googleauthorCho, Heeyoon-
dc.contributor.googleauthorHwang, Sun Jin-
dc.contributor.googleauthorJeon, Beomseo-
dc.contributor.googleauthorSeong, Mincheol-
dc.contributor.googleauthorYeom, Hosuck-
dc.contributor.googleauthorKang, Min Ho-
dc.contributor.googleauthorLim, Han Woong-
dc.contributor.googleauthorShin, Yong Un-
dc.relation.code2020047025-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidhwlim-


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