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Perioperative Symptomatic Venous Thromboembolism After Immediate Chemoprophylaxis in Patients With Pelvic and Lower-Extremity Fractures

Title
Perioperative Symptomatic Venous Thromboembolism After Immediate Chemoprophylaxis in Patients With Pelvic and Lower-Extremity Fractures
Author
박기철
Keywords
DEEP-VEIN THROMBOSIS; CLINICAL-PRACTICE GUIDELINE; RISK-FACTORS; PULMONARY-EMBOLISM; AMERICAN-COLLEGE; TOTAL HIP; TRAUMA; PREVENTION; KNEE; EPIDEMIOLOGY
Issue Date
2020-03
Publisher
NATURE PUBLISHING GROUP
Citation
SCIENTIFIC REPORTS, v. 10, no. 1, article no. 5431
Abstract
The purpose of this study was to investigate the incidence of symptomatic venous thromboembolism (VTE) after chemoprophylaxis in patients with pelvic and lower-extremity fractures, and to identify risk factors for VTEs in this subgroup of patients. To detect VTE, multi-detector computed tomography (CT) angiography was performed. Of 363 patients assessed, the incidence of symptomatic VTE was 12.4% (45 patients), and the incidence of symptomatic PE was 5.2% (19 patients). For the risk-factor analysis, a higher Charlson comorbidity index (p=0.037), and a history of external fixator application (p=0.007) were associated with increased VTE risk. Among patients who had VTE, male sex (p=0.017), and above-the-knee fractures (p=0.035) were associated with increased pulmonary embolism (PE) risk. In conclusions, the incidence of VTE in post-traumatic patients is not low after chemoprophylaxis. Risk factors for VTE and PE are different among patients with pelvic and lower-extremity fractures.
URI
https://www.nature.com/articles/s41598-020-62333-zhttps://repository.hanyang.ac.kr/handle/20.500.11754/162042
ISSN
2045-2322
DOI
10.1038/s41598-020-62333-z
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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