Perioperative symptomatic venous thromboembolism after immediate chemoprophylaxis in patients with pelvic and lower-extremity fractures
- Title
- Perioperative symptomatic venous thromboembolism after immediate chemoprophylaxis in patients with pelvic and lower-extremity fractures
- Author
- 이진규
- Keywords
- DEEP-VEIN THROMBOSIS; CLINICAL-PRACTICE GUIDELINE; RISK-FACTORS; PULMONARY-EMBOLISM; AMERICAN-COLLEGE; TOTAL HIP; TRAUMA; PREVENTION; KNEE; EPIDEMIOLOGY
- Issue Date
- 2020-03
- Publisher
- NATURE PUBLISHING GROUP
- Citation
- SCIENTIFIC REPORTS, v. 10, no. 1, article no. 5431
- Abstract
- The purpose of this study was to investigate the incidence of symptomatic venous thromboembolism (VTE) after chemoprophylaxis in patients with pelvic and lower-extremity fractures, and to identify risk factors for VTEs in this subgroup of patients. To detect VTE, multi-detector computed tomography (CT) angiography was performed. Of 363 patients assessed, the incidence of symptomatic VTE was 12.4% (45 patients), and the incidence of symptomatic PE was 5.2% (19 patients). For the risk-factor analysis, a higher Charlson comorbidity index (p=0.037), and a history of external fixator application (p=0.007) were associated with increased VTE risk. Among patients who had VTE, male sex (p=0.017), and above-the-knee fractures (p=0.035) were associated with increased pulmonary embolism (PE) risk. In conclusions, the incidence of VTE in post-traumatic patients is not low after chemoprophylaxis. Risk factors for VTE and PE are different among patients with pelvic and lower-extremity fractures.
- URI
- https://www.nature.com/articles/s41598-020-62333-zhttps://repository.hanyang.ac.kr/handle/20.500.11754/162041
- ISSN
- 2045-2322
- DOI
- 10.1038/s41598-020-62333-z
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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