Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임태호 | - |
dc.date.accessioned | 2021-04-08T01:47:45Z | - |
dc.date.available | 2021-04-08T01:47:45Z | - |
dc.date.issued | 2020-02 | - |
dc.identifier.citation | Clinical and Experimental Emergency Medicine, v. 7, no. 3, page. 183-189 | en_US |
dc.identifier.issn | 2383-4625 | - |
dc.identifier.uri | https://www.ceemjournal.org/journal/view.php?doi=10.15441/ceem.19.072 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/161262 | - |
dc.description.abstract | Objective: This study aimed to compare the diagnostic performance of cardiac biomarkers and to evaluate the optimal cut-off values for echocardiographic cardiac injury prediction in patients with carbon monoxide (CO) poisoning. Methods: This retrospective observational cohort study included adult patients with acute CO poisoning. Patients who did not undergo transthoracic echocardiography, which was used to define patients with cardiac injury (ejection fraction <55%), were excluded. The area under the curve was used to evaluate diagnostic performance for cardiac injury prediction. Mann-Whitney U, chi-square, and Fisher exact tests were used to analyze data. Results: After excluding the 27 patients who did not undergo echocardiography, 114 patients were included in the study. Fifteen (13.2%) patients had cardiac injury. The area under the curve values for the B-type natriuretic peptide, creatine kinase-myocardial band, and troponin I were 0.711 (95% confidence interval [CI], 0.527–0.895; P=0.011), 0.766 (95% CI, 0.607–0.926; P=0.001), and 0.801 (95% CI, 0.647–0.955; P<0.001), respectively, with optimal cut-off values of 330 pg/mL, 10.1 ng/mL, and 0.455 ng/mL, respectively. The sensitivity, specificity, and positive and negative predictive values of troponin I were 67%, 91%, 53%, and 95%, respectively. Conclusion: Troponin I showed the best diagnostic performance for predicting cardiac injury in patients with CO poisoning. A cut-off value of 0.455 ng/mL appeared optimal for cardiac injury prediction. However, further studies on cardiac biomarkers and other diagnostic tools in CO poisoning are needed given the low sensitivity of troponin I. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Korean Society of Emergency Medicine | en_US |
dc.subject | Carbon monoxide | en_US |
dc.subject | Poisoning | en_US |
dc.subject | Echocardiography | en_US |
dc.title | Diagnostic performance and optimal cut-off values of cardiac biomarkers for predicting cardiac injury in carbon monoxide poisoning | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 7 | - |
dc.identifier.doi | 10.15441/ceem.19.072 | - |
dc.relation.page | 183-189 | - |
dc.relation.journal | Clinical and Experimental Emergency Medicine | - |
dc.contributor.googleauthor | Park, Jun Hwan | - |
dc.contributor.googleauthor | Heo, Ran | - |
dc.contributor.googleauthor | Kang, Hyunggoo | - |
dc.contributor.googleauthor | Oh, Jaehoon | - |
dc.contributor.googleauthor | Lim, Tae Ho | - |
dc.contributor.googleauthor | Ko, Byuk Sung | - |
dc.relation.code | 2020004469 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | erthim | - |
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