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dc.contributor.advisor신숭훈-
dc.contributor.author오수민-
dc.date.accessioned2021-02-24T16:04:43Z-
dc.date.available2021-02-24T16:04:43Z-
dc.date.issued2021. 2-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/159005-
dc.identifier.urihttp://hanyang.dcollection.net/common/orgView/200000485419en_US
dc.description.abstractDirect functionalization of inert C-H bonds is an attractive strategy and therefore have drawn intense interest. To implement such a strategy for regioselective functionalization of phenols, we introduced herein N-(acyloxy)indole as electrophilic, umpoled indole derivatives. In this presentation, we developed a new protocol for a general synthesis of N-(acyloxy)indoles, based on the electrophilic cyclization of (o-alkynyl)phenylhydroxylamines. With an easy access to a variety of N-(acyloxy)indoles, we developed a Cu(I) catalyzed ortho-selective coupling of phenols with the umpoled indoles. The [Cu(OTf)]2·C6H6 system was extremely reactive and catalyzed the coupling at a very low loading (0.1 - 0.01 mol%) and at room temperature. The unusual C2-regioselectivity was rationalized by a sequence comprising N-substitution, followed by [3,3]-sigmatropic rearrangement.-
dc.publisher한양대학교-
dc.titleCu(I)-Catalyzed ortho-Selective Cross-Coupling of Phenols with Electrophilic Indoles-
dc.title.alternativeCu(I)-촉매에 의한 친전자성 인돌과 페놀의 위치선택적 짝지움반응-
dc.typeTheses-
dc.contributor.googleauthor오수민-
dc.contributor.alternativeauthor오수민-
dc.sector.campusS-
dc.sector.daehak대학원-
dc.sector.department화학과-
dc.description.degreeMaster-
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GRADUATE SCHOOL[S](대학원) > CHEMISTRY(화학과) > Theses (Master)
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