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dc.contributor.author이경석-
dc.date.accessioned2021-02-15T06:07:39Z-
dc.date.available2021-02-15T06:07:39Z-
dc.date.issued2019-12-
dc.identifier.citationCLINICAL RESPIRATORY JOURNAL, v. 14, no.3, page. 250-259en_US
dc.identifier.issn1752-6981-
dc.identifier.issn1752-699X-
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/full/10.1111/crj.13124-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/158135-
dc.description.abstractIntroduction Rhinitis and obstructive sleep apnea syndrome (OSAS) are different diseases, but have some similar risk factors. Objective The aims of this study were to compare the risk factors and clinical biomarkers for rhinitis and OSAS in children. Methods We examined 3917 children (age 4-13 years) who were enrolled in a cross-sectional study conducted in Seongnam, Korea. Their parents completed the Pediatric Sleep Questionnaire (PSQ) for evaluation of OSAS and the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire for evaluation of rhinitis. Clinical biomarkers, including total eosinophil count and neutrophil-lymphocyte ratio (NLR), were measured in a subset of these children. Results OSAS and rhinitis had prevalences of 4.0% and 43.5%, respectively. Body mass index (P < 0.001) and prematurity (P = 0.016) were significantly associated with OSAS, but not with rhinitis. Higher parental education and income increased the risk for rhinitis, but decreased the risk for OSAS. Having more siblings and birth by Cesarean delivery decreased the risk for rhinitis, but living in a new household increased the risk for rhinitis. A short distance of the residence to a main road during pregnancy significantly increased the risk of OSAS. Males, increased exposure to mould, and firstborns had increased risk of OSAS and rhinitis. The NLR was higher in OSAS patients than in those with allergic rhinitis (P = 0.001). Conclusion OSAS and rhinitis shared some risk factors, whereas other factors had inverse association with the two disorders. These results imply that different strategies might be used for prevention of rhinitis and OSAS.en_US
dc.description.sponsorshipSeongnam Atopy Project 2015en_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.subjectobstructive sleep apnea syndromeen_US
dc.subjectprevalenceen_US
dc.subjectrhinitisen_US
dc.subjectrisk factoren_US
dc.titleShared and unique individual risk factors and clinical biomarkers in children with allergic rhinitis and obstructive sleep apnea syndromeen_US
dc.typeArticleen_US
dc.relation.no00-
dc.relation.volume2019-
dc.identifier.doi10.1111/crj.13124-
dc.relation.page1-10-
dc.relation.journalCLINICAL RESPIRATORY JOURNAL-
dc.contributor.googleauthorHa, Eun Kyo-
dc.contributor.googleauthorPark, Jun Hyeong-
dc.contributor.googleauthorLee, Seung Jin-
dc.contributor.googleauthorYon, Dong Keon-
dc.contributor.googleauthorKim, Ju Hee-
dc.contributor.googleauthorJee, Hye Mi-
dc.contributor.googleauthorLee, Kyung Suk-
dc.contributor.googleauthorSung, Myongsoon-
dc.contributor.googleauthorKim, Mi Ae-
dc.contributor.googleauthorShin, Youn Ho-
dc.relation.code2019043875-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidnoquit-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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