Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 송무곤 | - |
dc.date.accessioned | 2021-01-20T01:54:55Z | - |
dc.date.available | 2021-01-20T01:54:55Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.citation | Blood Research, v. 54, no. 4, page. 244-252 | en_US |
dc.identifier.issn | 2287-979X | - |
dc.identifier.issn | 2288-0011 | - |
dc.identifier.uri | https://www.bloodresearch.or.kr/journal/view.html?doi=10.5045/br.2019.54.4.244 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/157201 | - |
dc.description.abstract | Background Systemic inflammatory response can be associated with the prognosis of diffuse large B cell lymphoma (DLBCL). We investigated the systemic factors significantly related to clinical outcome in relapsed/refractory DLBCL.. Methods In 242 patients with DLBCL, several factors, including inflammatory markers were analyzed. We assessed for the correlation between the survivals [progression-free surviv-al (PFS) and overall survival (OS)] and prognostic factors. Results In these patients, a high derived neutrophil/lymphocyte ratio (dNLR) (PFS, HR=2.452, P=0.002; OS, HR=2.542, P=0.005), high Glasgow Prognostic Score (GPS) (PFS, HR=2.435, P=0.002; OS, HR=2.621, P=0.002), and high NCCN-IPI (PFS, HR=2.836, P=0.003; OS, HR=2.928, P=0.003) were significantly associated with survival in multi-variate analysis. Moreover, we proposed a risk stratification model based on dNLR, GPS, and NCCN-IPI, thereby distributing patients into 4 risk groups. There were significant differences in survival among the 4 risk groups (PFS, P<0.001; OS, P<0.001). Conclusion In conclusion, dNLR, GPS, and NCCN-IPI appear to be excellent prognostic parameters for survival in relapsed/refractory DLBCL. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Korean Society of Hematology | en_US |
dc.subject | Derived neutrophil/lymphocyte ratio | en_US |
dc.subject | Glasgow prognostic score | en_US |
dc.subject | DLBCL | en_US |
dc.title | Clinical impacts of inflammatory markers and clinical factors in patients with relapsed or refractory diffuse large B-cell lymphoma | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 54 | - |
dc.identifier.doi | 10.5045/br.2019.54.4.244 | - |
dc.relation.page | 244-252 | - |
dc.relation.journal | Blood Research | - |
dc.contributor.googleauthor | Kim, Do-Young | - |
dc.contributor.googleauthor | Song, Moo-Kon | - |
dc.contributor.googleauthor | Chun, Joo-Seop | - |
dc.contributor.googleauthor | Shin, Ho-Jin | - |
dc.contributor.googleauthor | Yang, Deok Hwan | - |
dc.contributor.googleauthor | Lim, Sung-Nam | - |
dc.contributor.googleauthor | Oh, Sung-Yong | - |
dc.relation.code | 2019011979 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | song9676 | - |
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