Investigation of Systolic Blood Pressure, Diastolic Blood Pressure, and Pulse Pressure in Living Kidney Donors After Donor Nephrectomy
- Title
- Investigation of Systolic Blood Pressure, Diastolic Blood Pressure, and Pulse Pressure in Living Kidney Donors After Donor Nephrectomy
- Author
- 윤영은
- Keywords
- LONG-TERM CONSEQUENCES; ARTERIAL STIFFNESS; CARDIOVASCULAR-DISEASE; RENAL-FUNCTION; RISK-FACTOR; FOLLOW-UP; DONATION
- Issue Date
- 2019-10
- Publisher
- ELSEVIER SCIENCE INC
- Citation
- TRANSPLANTATION PROCEEDINGS, v. 51, no. 8, Page. 2533-2538
- Abstract
- Kidney transplants from living donors have increased, but few studies have examined the long-term risks of live donor nephrectomy. This is the first study to report the blood pressure (BP) changes associated with cardiovascular disease and linked to chronic kidney disease (CKD) 1 year after live donor nephrectomy. This study examined a prospective cohort of patients who underwent donor nephrectomy between March 1, 2006, and December 31, 2016, at the Severance Hospital, Seoul, South Korea. CKD was defined as a glomerular filtration rate (GFR) of < 60 mL/min/1.73m(2). Patients with a history of hypertension or CKD or an estimated GFR < 60 mL/min/1.73m(2) were excluded; those examined after 1 year post-nephrectomy were included in the study population. Among 420 patients who underwent donor nephrectomy, 137 (32.6%) developed a first-time onset of a GFR < 60 mL/min/1.73m(2) by the first year after surgery. After propensity score-matching the age, systolic BP (P < .001) and pulse pressure (P = .006) were significantly associated with the groups with newly developed CKD. Systolic BP and pulse pressure decreased significantly at 1 year after donor nephrectomy. These differences decreased after donor nephrectomy, possibly lowering the risk of cardiovascular disease.
- URI
- https://www.sciencedirect.com/science/article/pii/S004113451930257X?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/154699
- ISSN
- 0041-1345; 1873-2623
- DOI
- 10.1016/j.transproceed.2019.03.064
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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