Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 한동수 | - |
dc.date.accessioned | 2020-09-07T00:33:01Z | - |
dc.date.available | 2020-09-07T00:33:01Z | - |
dc.date.issued | 2019-08 | - |
dc.identifier.citation | PLOS ONE, v. 14, no. 8, article no. e0220660 | en_US |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220660 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/153588 | - |
dc.description.abstract | Controversies exist regarding the impact of age on gastric cancer-related mortality according to cancer stage. In our prospective cohort study, we evaluated the impact of age on stage-specific mortality in patients with gastric cancer. Between 2002 and 2006, patients with newly diagnosed gastric cancer were recruited from two university-affiliated hospitals in Korea. Follow-up data were updated regularly based on medical records and telephone surveys. Patients were classified into four subgroups according to age: < 50, 50-59, 60-69, and 70-79 years. A total of 448 patients were followed up for 81.6 months (interquartile range, 25.0-139.3 months). The number of patients with stage I, II, III, and IV disease was 247, 74, 88, and 39, respectively. Overall, age was an independent risk factor for gastric cancer-specific mortality (hazard ratio [HR], [95% confidence interval (CI)]: 1.53 [0.91-2.57], 1.88 [1.21-2.91], and 2.64 [1.69-4.14] in the 50-59, 60-69, and 70-79 years groups, respectively, with the < 50 years group as reference). In patients with stage I and II gastric cancer, the 70-79 years group was associated with a significantly higher rate of cancer-specific mortality than the < 50 years group (stage I: HR [95% CI], 9.55 [2.11-43.12]; stage II: HR [95% CI], 7.17 [2.32-22.18]). However, age was not an independently associated factor for cancer-specific mortality in patients with stage III and IV gastric cancer. Although age was an independent risk factor for gastric cancer-related mortality in patients with gastric cancer, its impact may differ depending on the stage of cancer. | en_US |
dc.description.sponsorship | This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number: 2017R1D1A3B03032996, grant receiver: HJK). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | en_US |
dc.language.iso | en | en_US |
dc.publisher | PUBLIC LIBRARY SCIENCE | en_US |
dc.subject | CLINICOPATHOLOGICAL CHARACTERISTICS | en_US |
dc.subject | PROGNOSIS | en_US |
dc.subject | SURVIVAL | en_US |
dc.subject | YOUNG | en_US |
dc.subject | OUTCOMES | en_US |
dc.subject | MUCOSA | en_US |
dc.subject | SCORE | en_US |
dc.title | Impact of age on stage-specific mortality in patients with gastric cancer: A long-term prospective cohort study | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 14 | - |
dc.identifier.doi | 10.1371/journal.pone.0220660 | - |
dc.relation.page | 220660-220675 | - |
dc.relation.journal | PLOS ONE | - |
dc.contributor.googleauthor | Lee, Jae Gon | - |
dc.contributor.googleauthor | Kim, Shin Ah | - |
dc.contributor.googleauthor | Eun, Chang Soo | - |
dc.contributor.googleauthor | Han, Dong Soo | - |
dc.contributor.googleauthor | Kim, Young Sung | - |
dc.contributor.googleauthor | Choi, Bo Youl | - |
dc.contributor.googleauthor | Song, Kyu Sang | - |
dc.contributor.googleauthor | Kim, Hyun Ja | - |
dc.contributor.googleauthor | Park, Chan Hyuk | - |
dc.relation.code | 2019042142 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hands | - |
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