Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김한준 | - |
dc.date.accessioned | 2020-08-05T06:45:59Z | - |
dc.date.available | 2020-08-05T06:45:59Z | - |
dc.date.issued | 2019-07 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF STEM CELLS, v. 12, NO 2, Page. 183-194 | en_US |
dc.identifier.issn | 2005-3606 | - |
dc.identifier.issn | 2005-5447 | - |
dc.identifier.uri | http://www.ijstemcell.com/journal/view.html?doi=10.15283/ijsc18055 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/152054 | - |
dc.description.abstract | Cholangiopathies are rare diseases of the bile duct with high mortality rates. The current treatment for cholangiopathies is liver transplantation, but there are significant obstacles including a shortage of donors and a high risk of complications. Currently, there is only one available medicine on the market targeting cholangiopathies, and the results have been inadequate in clinical therapy. To overcome these obstacles, many researchers have used human induced pluripotent stem cells (hPSC) as a source for cholangiocyte-like cell generation and have incorporated advances in bioprinting to create artificial bile ducts for implantation and transplantation. This has allowed the field to move dramatically forward in studies of biliary regenerative medicine. In this review, the authors provide an overview of cholangiocytes, the organogenesis of the bile duct, cholangiopathies, and the current treatment and advances that have been made that are opening new doors to the study of cholangiopathies. | en_US |
dc.description.sponsorship | This research was supported by Grants from the Medical Research Center (NRF-2017R1A5A2015395), the Bio & Medical Technology Development Program (2018M3A9H1023910, 2018M3A9H3022412) funded by the National Research Foundation of Korea (NRF) of the Ministry of Education, Science and Technology (MEST), and the Technology Innovation Program or Industrial Strategic Technology Development Program (10063334, Vascularized 3D tissue (liver/heart, cancer chip for evaluation of drug efficacy and toxicity) funded by the Ministry of Trade, Industry, & Energy of Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KOREAN SOC STEM CELL RESEARCH | en_US |
dc.subject | Cholangiocytes | en_US |
dc.subject | Cholangiopathies | en_US |
dc.subject | Biliary regeneration | en_US |
dc.subject | Human derived pluripotent stem cells | en_US |
dc.subject | Bioprinting | en_US |
dc.subject | Stem cell therapy | en_US |
dc.title | Regenerative Medicine of the Bile Duct: Beyond the Myth | en_US |
dc.type | Article | en_US |
dc.relation.no | 2 | - |
dc.relation.volume | 12 | - |
dc.identifier.doi | 10.15283/ijsc18055 | - |
dc.relation.page | 183-194 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF STEM CELLS | - |
dc.contributor.googleauthor | Buisson, Elina Maria | - |
dc.contributor.googleauthor | Jeong, Jaemin | - |
dc.contributor.googleauthor | Kim, Han Joon | - |
dc.contributor.googleauthor | Choi, Dongho | - |
dc.relation.code | 2019039964 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | thicknyh | - |
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