Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정운용 | - |
dc.date.accessioned | 2020-06-04T05:35:07Z | - |
dc.date.available | 2020-06-04T05:35:07Z | - |
dc.date.issued | 2019-07 | - |
dc.identifier.citation | CHEMICAL COMMUNICATIONS, v. 55, no. 52, Page. 7466-7469 | en_US |
dc.identifier.issn | 1359-7345 | - |
dc.identifier.issn | 1364-548X | - |
dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2019/CC/C9CC01944H | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/151446 | - |
dc.description.abstract | We developed a molecular beacon targeting miR-141-3p, aberrantly increased in 5-fluorouracil-resistant colorectal cancer cells (R-CRCCs). It consists of a fluorophore-labeled oligonucleotide, antisense to miR-141-3p, and a quencher. It detected R-CRCCs and recovered the chemosensitivity of them to 5-fluorouracil by hybridization with miR-141-3p, which is applicable to cancer treatment. | en_US |
dc.description.sponsorship | This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2013R1A1A1076069, NRF-2016R1D1A1B03936192, NRF-2017R1A2B2002042, NRF-2017R1C1B1008436, and NRF-2017R1D1A3B03036431). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ROYAL SOC CHEMISTRY | en_US |
dc.subject | CHEMORESISTANCE | en_US |
dc.title | Theragnosis by a miR-141-3p molecular beacon: simultaneous detection and sensitization of 5-fluorouracil resistant colorectal cancer cells through the activation of the TRIM13-associated apoptotic pathway | en_US |
dc.type | Article | en_US |
dc.relation.volume | 55 | - |
dc.identifier.doi | 10.1039/c9cc01944h | - |
dc.relation.page | 7466-7469 | - |
dc.relation.journal | CHEMICAL COMMUNICATIONS | - |
dc.contributor.googleauthor | Moon, Sung Ung | - |
dc.contributor.googleauthor | Park, Yongkeun | - |
dc.contributor.googleauthor | Park, Min Geun | - |
dc.contributor.googleauthor | Song, Sung Kyu | - |
dc.contributor.googleauthor | Jeong, Seok Hoo | - |
dc.contributor.googleauthor | Lee, Yong Seung | - |
dc.contributor.googleauthor | Heo, Hye Jung | - |
dc.contributor.googleauthor | Jung, Woon Yong | - |
dc.contributor.googleauthor | Kim, Soonhag | - |
dc.relation.code | 2019001551 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | pathjwy | - |
dc.identifier.orcid | http://orcid.org/0000-0003-4786-2823 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.