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Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 류성언 | - |
| dc.date.accessioned | 2020-04-21T05:33:26Z | - |
| dc.date.available | 2020-04-21T05:33:26Z | - |
| dc.date.issued | 2019-07 | - |
| dc.identifier.citation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v. 29, NO 14, Page. 1746-1748 | en_US |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.issn | 1464-3405 | - |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0960894X1930318X?via%3Dihub | - |
| dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/151154 | - |
| dc.description.abstract | Structure based virtual screening attempts to discover DUSP1 inhibitors have yielded a scaffold featuring benzoxazole and acylthiourea pharmacophore. A series of its analogues were synthesized to explore structure activity relationship (SAR) of DUSP1 inhibition. | en_US |
| dc.description.sponsorship | This research was supported by a grant from KRIBB Research Initiative Program. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | en_US |
| dc.subject | Dual specificity phosphatase | en_US |
| dc.subject | Mitogen-activated protein kinase | en_US |
| dc.subject | Enzyme inhibition | en_US |
| dc.subject | Structure activity relationship | en_US |
| dc.subject | Cancer | en_US |
| dc.title | Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition | en_US |
| dc.type | Article | en_US |
| dc.relation.no | 14 | - |
| dc.relation.volume | 29 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2019.05.021 | - |
| dc.relation.page | 1746-1748 | - |
| dc.relation.journal | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.contributor.googleauthor | Kim, Bo Yeon | - |
| dc.contributor.googleauthor | Yoon, Ji Hee | - |
| dc.contributor.googleauthor | Kim, Myeongbin | - |
| dc.contributor.googleauthor | Kim, Jae Nyoung | - |
| dc.contributor.googleauthor | Park, Hwangseo | - |
| dc.contributor.googleauthor | Ryu, Seong Eon | - |
| dc.contributor.googleauthor | Lee, Sangku | - |
| dc.relation.code | 2019000635 | - |
| dc.sector.campus | S | - |
| dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
| dc.sector.department | DEPARTMENT OF BIOENGINEERING | - |
| dc.identifier.pid | ryuse | - |
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- COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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