168 0

Predicting the Therapeutic Efficacy of Laser Peripheral Iridotomy for Individuals With Asymptomatic Narrow Angle: The Triple Hump Sign

Title
Predicting the Therapeutic Efficacy of Laser Peripheral Iridotomy for Individuals With Asymptomatic Narrow Angle: The Triple Hump Sign
Author
이원준
Keywords
primary angle-closure suspect; laser peripheral iridotomy; intraocular pressure; anterior segment optical coherence tomography; triple hump sign
Issue Date
2019-02
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Citation
JOURNAL OF GLAUCOMA, v. 28, NO 2, Page. 125-130
Abstract
Purpose: To evaluate the clinical efficacy of a novel screening sign [ie, the triple hump (TH) sign] for prediction of laser peripheral iridotomy (LPI)'s intraocular pressure (IOP)-lowering effectiveness in subjects with asymptomatic narrow angles. Methods: This cross-sectional study was conducted from 2010 to 2015 in a hospital setting. Eighty-four eyes of 84 primary angle-closure suspect (PACS) patients were imaged before LPI using anterior segment optical coherence tomography. The "positive-TH sign" was defined, on anterior segment optical coherence tomography-generated cross-sectional scans, as the characteristic configuration formed by the angulations between the crystalline lens's central anterior surface and both sides of the iris pigment epithelium. After LPI, the extent of IOP reduction was compared between the positive- and negative-TH groups. Results: The positive-TH eyes did not significantly differ from the negative-TH ones in pre-LPI IOP (P = 0.200). In the positive-TH group, IOP decreased significantly after LPI (by 6.42% +/- 17.96%, from 14.07 +/- 3.11 to 12.88 +/- 2.65 mm Hg, P = 0.002). In the negative-TH group, IOP did not change significantly after LPI (by 4.66% +/- 25.97%, from 13.23 +/- 2.42 to 13.52 +/- 3.01 mm Hg, P = 0.624). Conclusion: PACS eyes indicating the positive-TH sign showed, at post-LPI 1 month, a greater IOP decrease. On this basis, the TH sign may be a useful screening tool for predicting the effect of LPI and determining the treatment plan in PACS patients.
URI
https://insights.ovid.com/crossref?an=00061198-201902000-00006https://repository.hanyang.ac.kr/handle/20.500.11754/139409
ISSN
1057-0829; 1536-481X
DOI
10.1097/IJG.0000000000001157
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE