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dc.contributor.author배옥남-
dc.date.accessioned2020-03-12T06:15:43Z-
dc.date.available2020-03-12T06:15:43Z-
dc.date.issued2004-03-
dc.identifier.citationJournal of Toxicology and Public Health, v. 20, No. 1, Page. 137-142en_US
dc.identifier.issn1976-8257-
dc.identifier.issn2234-2753-
dc.identifier.urihttp://www.dbpia.co.kr/journal/articleDetail?nodeId=NODE00544171&language=ko_KR-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/136800-
dc.description.abstractWe investigated the effects of plant vinegar on platelets and blood coagulation system. Plant vinegar inhibited in vitro platelet aggregation in a concentration dependent manner, when platelets were activated by thrombin and collagen. In addition, plant vinegar showed inhibitory effects on the serotonin secretion induced by thrombin in a concentration dependent manner. However, treatment with plant vinegar to platelets did not induce any cytotoxicity, as determined by the release of lactate dehydrogenase. Plant vinegar did not change the coagulation parameters such as activated partial thromboplastin time (aPTT) and prothrombin time (PT) using rat citrated plasma. In vivo study revealed that, treatment with plant vinegar prolonged the bleeding time from mouse tail. All these results suggest that plant vinegar might improve blood hemostasis mediated via antiplatelet activities.en_US
dc.language.isoen_USen_US
dc.publisher한국독성학회en_US
dc.subjectPlant vinegaren_US
dc.subjectPlateletsen_US
dc.subjectCytotoxicityen_US
dc.subjectAntiplatelet activityen_US
dc.subjectCardiovascular diseaseen_US
dc.title목초액의 혈소판 응집억제를 통한 혈행개선 작용에 관한 연구en_US
dc.title.alternativeImprovement of Haemostasis Mediated by Anti-Platelet Activities by Plant Vinegaren_US
dc.typeArticleen_US
dc.relation.no2-
dc.relation.volume20-
dc.relation.page137-142-
dc.relation.journal한국독성학회지-
dc.contributor.googleauthor김영대-
dc.contributor.googleauthor배옥남-
dc.contributor.googleauthor정승민-
dc.contributor.googleauthor정진호-
dc.relation.code2012210963-
dc.sector.campusE-
dc.sector.daehakCOLLEGE OF PHARMACY[E]-
dc.sector.departmentDEPARTMENT OF PHARMACY-
dc.identifier.pidonbae-
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COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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