파라메트릭 대퇴골 모델과 반응표면법을 이용한 대퇴골의 기하학적 형상과 경부 골절과의 관계 분석

Abstract

Previous in-vitro studies to analyze the correlations between the femoral morphology and femoral neck fractures (FNF) have relied on either mechanical testing or finite element methods. However, these methods have not been extensively applied to analyzing the effect of the morphologic variations of femurs. It is mainly due to the lack of various femoral samples from both patients and cadavers, or to the computational limitation in changing the shape of the femoral models. I present a novel parametric morphing approach to obtain various finite elemental models from a subject-specific femur to obtain a predictive analytic model on FNF. To analyze the effects of the geometric parameters on the fractures, I apply the response surface methodology to the result obtained from the finite element analysis on the samples. Since I consider the interaction effects among the parameters, the analytic model of FNF may be more reliable in predicting the risk of the fractures than the others presented in previous studies. I verify the reliability of our predictive model by comparing with the actual cadaveric experimental results from an in-vitro study.