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DC FieldValueLanguage
dc.contributor.author황환식-
dc.date.accessioned2020-01-13T07:50:20Z-
dc.date.available2020-01-13T07:50:20Z-
dc.date.issued2019-06-
dc.identifier.citationJOURNAL OF CLINICAL MEDICINE, v. 8, NO 7, no. 950en_US
dc.identifier.issn2077-0383-
dc.identifier.urihttps://www.mdpi.com/2077-0383/8/7/950-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/121759-
dc.description.abstractWe aimed to investigate how body weight fluctuation affects the risk of developing type 2 diabetes by conducting a nationwide cohort study. A total of 3,855,884 participants from the National Health Insurance System health check-up data from 2012 were included in this study, and follow-up continued until 2016. Body weight was measured at least thrice between 2009 and 2012. Body weight variability (BWV) was estimated using average successive variability (ASV) indices. Cox proportional hazards regression models were used to evaluate the association of BWV with the risk of type 2 diabetes using hazard ratios (HRs) and 95% confidence intervals (CIs). Body weight fluctuation was associated with a higher risk of incident diabetes after adjustment for confounders (HR 1.10, 95% CI 1.07, 1.12 in the highest BWV quartile compared to the lowest). Regardless of the weight change status, the highest ASV quartile of BWV increased the risk for diabetes. Even subjects with a normal glucose tolerance status and those aged under 65 years had a higher risk of diabetes if their body weight highly fluctuated during the follow-up years. Our results suggest that body weight variability is an independent risk factor for diabetes. It is important to pay attention to frequent body weight fluctuations.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectaverage successive variabilityen_US
dc.subjectbody weight fluctuationen_US
dc.subjectcohort studyen_US
dc.subjectweight changeen_US
dc.subjecttype 2 diabetesen_US
dc.titleBody Weight Fluctuation as a Risk Factor for Type 2 Diabetes: Results from a Nationwide Cohort Studyen_US
dc.typeArticleen_US
dc.relation.no950-
dc.relation.volume8-
dc.identifier.doi10.3390/jcm8070950-
dc.relation.page1-11-
dc.relation.journalJOURNAL OF CLINICAL MEDICINE-
dc.contributor.googleauthorPark, Kye-Yeung-
dc.contributor.googleauthorHwang, Hwan-Sik-
dc.contributor.googleauthorCho, Kyung-Hwan-
dc.contributor.googleauthorHan, Kyungdo-
dc.contributor.googleauthorNam, Ga Eun-
dc.contributor.googleauthorKim, Yang Hyun-
dc.contributor.googleauthorKwon, Yeongkeun-
dc.contributor.googleauthorPark, Yong-Gyu-
dc.relation.code2019044887-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidfmhwang-
dc.identifier.researcherIDK-6228-2017-
dc.identifier.orcidhttps://orcid.org/0000-0002-6248-7411-


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