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dc.contributor.author이원준-
dc.date.accessioned2019-12-10T20:49:28Z-
dc.date.available2019-12-10T20:49:28Z-
dc.date.issued2018-12-
dc.identifier.citationAMERICAN JOURNAL OF OPHTHALMOLOGY, v. 196, page. 65-71en_US
dc.identifier.issn0002-9394-
dc.identifier.issn1879-1891-
dc.identifier.urihttps://www.ajo.com/article/S0002-9394(18)30447-1/fulltext-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/121203-
dc.description.abstractPURPOSE: To evaluate patterns of glaucomatous structural progression using the combined retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) event-based progression analysis feature provided by spectral-domain optical coherence tomography (SD-OCT)'s - (GPA) software.DESIGN: Retrospective observational case series.METHODS: Seventy-nine (79) patients were identified with open-angle glaucoma (OAG) showing clinically confirmed structural progression within a minimum 3-year follow-up period. For each eye, RNFL and GCIPL GPA data were obtained from serial SD-OCT data from 2012 to 2017. An integrated GPA map thereafter was merged by vascular landmark guided superimposition of RNFL and GCIPL GPA event-based progression maps onto the RNFL imagery (resulting in what we call the GPA PanoMap). The GPA PanoMap progression patterns were classified as (1) RNFL-only, (2) GCIPL-only, (3) concurrent (both RNFL and GCIPL), (4) GCIPL after RNFL, and (5) RNFL after GCIPL. The locations of structural progression were classified, based on an earlier schematic model, as (1) superior vulnerability zone (SVZ), (2) papillomacular bundle (PM), (3) macular vulnerability zone (MVZ), and (4) inferoinferior portion. Structural progression patterns on the GPA PanoMap were evaluated according to the location of progression. Among the eyes with progression in the inferior hemiretina, structural progression patterns on the GPA PanoMap were evaluated according to the baseline structural damage.RESULTS: On the GPA PanoMap, when structural progression was located in the SVZ or inferoinferior portion, it was detected only in the RNFL area; when progression was located in the PM or MVZ, various patterns were observed, among which the concurrent pattern was the majority in both areas (43.8% and 45.6% in the PM and MVZ, respectively). Among the eyes with progression in the inferior hemiretina (n = 66), the location of progression varied but did not differ significantly according to the baseline deviation map (P =.440). The progression patterns of MVZ were significantly different among the baseline deviation map patterns (P = .023); however, all of the progression patterns of the inferoinferior portion were RNFL-only.CONCLUSION: The various progression patterns were confirmed according to the locations and baseline patterns of glaucomatous structural change on the integrated GPA map (GPA PanoMap). Combined use of RNFL and GCIPL GPA or the GPA PanoMap could be useful for determination of structural progression and understanding of its patterns in patients with glaucoma.(C) 2018 Elsevier Inc. All rights reserved.en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.subjectOPTICAL COHERENCE TOMOGRAPHYen_US
dc.subjectGLAUCOMA DIAGNOSTIC-ACCURACYen_US
dc.subjectTREND-BASED ANALYSISen_US
dc.subjectTHICKNESSen_US
dc.subjectDAMAGEen_US
dc.subjectMAPSen_US
dc.subjectEYESen_US
dc.titleCombined Use of Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Event-based Progression Analysisen_US
dc.typeArticleen_US
dc.relation.volume196-
dc.identifier.doi10.1016/j.ajo.2018.08.007-
dc.relation.page65-71-
dc.relation.journalAMERICAN JOURNAL OF OPHTHALMOLOGY-
dc.contributor.googleauthorLee, Won June-
dc.contributor.googleauthorNa, Kyeong Ik-
dc.contributor.googleauthorHa, Ahnul-
dc.contributor.googleauthorKim, Young Kook-
dc.contributor.googleauthorJeoung, Jin Wook-
dc.contributor.googleauthorPark, Ki Ho-
dc.relation.code2018000398-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidwjoon0208-
dc.identifier.researcherIDY-8207-2018-
dc.identifier.orcidhttp://orcid.org/0000-0002-3506-7139-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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