Postpartum Superior Sagittal Sinus Thrombosis: A Case Report

Abstract

Cerebral venous sinus thrombosis (CVST) is a rare disease. Early diagnosis and treatment are important, as CVST is potentially fatal. Pregnancy and puerperium are known risk factors for CVST. Here, we report the case of a patient who developed superior sagittal sinus thrombosis after a normal vaginal delivery. A 20-year-old woman presented with a headache and seizures two days after a normal vaginal delivery. Initially, brain computed tomography (CT) showed asubarachnoid hemorrhage in the right parietal lobe and sylvian fssure, together with mild cerebral edema. CT angiography revealed superior sagittal sinus thrombosis. Multiple micro-infarctions were seen on diffusion-weighted magneticresonance images. An intravenous infusion of heparin and mannitol was administered immediately. Two days after treatment initiation, the patient showed sudden neurological deterioration, with left-sided hemiplegia. Brain CT showed moderate brain edema and hemorrhagic densities. Emergency decompressive craniectomy was performed, and heparin wasre-administered on post-operative day (POD) 1. On POD 9, the patient’s mental state improved from stupor to drowsy, butthe left-sided hemiplegia persisted. CT angiography showed that the superior sinus thrombosis had decreased. Superiorsagittal sinus thrombosis is an uncommon complication, with an unfavorable outcome, after delivery. Timely diagnosisand treatment are important for preventing neurological deterioration.