Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박혜진 | - |
dc.date.accessioned | 2019-12-09T18:50:52Z | - |
dc.date.available | 2019-12-09T18:50:52Z | - |
dc.date.issued | 2018-10 | - |
dc.identifier.citation | CANCER RESEARCH AND TREATMENT, v. 50, no. 4, page. 1316-1323 | en_US |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.issn | 2005-9256 | - |
dc.identifier.uri | https://www.e-crt.org/journal/view.php?doi=10.4143/crt.2017.575 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/120367 | - |
dc.description.abstract | PurposeThe aim of this study is to compare the treatment outcomes of breast conserving surgery (BCS) plus radiotherapy (RT) versus mastectomy for patients with pT1-2N1 triple-negative breast cancer (TNBC).Materials and MethodsUsing two multicenter retrospective studies on breast cancer, a pooled analysis was performed among 320 patients with pT1-2N1 TNBC. All patients who underwent BCS (n=212) received whole breast RT with or without regional nodal RT, while none who underwent mastectomy (n=108) received it. All patients received taxane-based adjuvant chemotherapy. The median follow-up periods were 65 months in the BCS+RT group, and 74 months in the mastectomy group.ResultsThe median age of all patients was 48 years (range, 24 to 70 years). Mastectomy group had more patients with multiple tumors (p < 0.001), no lymphovascular invasion (p=0.001), higher number of involved lymph node (p=0.028), and higher nodal ratio. 0.2 (p=0.037). Other characteristics were not significantly different between the two groups. The 5-year locoregional recurrence-free, disease-free, and overall survival rates of BCS+RT group versus mastectomy group were 94.6% versus 87.7%, 89.5% versus 80.4%, and 95.0% versus 87.8%, respectively, and the differences were statistically significant after adjusting for covariates (p=0.010, p=0.006, and p=0.005, respectively).ConclusionIn pT1-2N1 TNBC, breast conservation therapy achieved better locoregional recurrence-free, disease-free, and overall survival rates compared with mastectomy. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | KOREAN CANCER ASSOCIATION | en_US |
dc.subject | Triple negative breast neoplasms | en_US |
dc.subject | Breast conservation therapy | en_US |
dc.subject | Mastectomy | en_US |
dc.title | Breast Conservation Therapy versus Mastectomy in Patients with T1-2N1 Triple-Negative Breast Cancer: Pooled Analysis of KROG 14-18 and 14-23 | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 50 | - |
dc.identifier.doi | 10.4143/crt.2017.575 | - |
dc.relation.page | 1316-1323 | - |
dc.relation.journal | CANCER RESEARCH AND TREATMENT | - |
dc.contributor.googleauthor | Kim, Kyubo | - |
dc.contributor.googleauthor | Park, Hae Jin | - |
dc.contributor.googleauthor | Shin, Kyung Hwan | - |
dc.contributor.googleauthor | Kim, Jin Ho | - |
dc.contributor.googleauthor | Choi, Doo Ho | - |
dc.contributor.googleauthor | Park, Won | - |
dc.contributor.googleauthor | Ahn, Seung Do | - |
dc.contributor.googleauthor | Kim, Su Ssan | - |
dc.contributor.googleauthor | Kim, Dae Yong | - |
dc.contributor.googleauthor | Kim, Tae Hyun | - |
dc.relation.code | 2018004348 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | haejinpark | - |
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