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dc.contributor.author한명훈-
dc.date.accessioned2019-12-08T14:52:19Z-
dc.date.available2019-12-08T14:52:19Z-
dc.date.issued2018-07-
dc.identifier.citationSCIENTIFIC REPORTS, v. 8, Article no. 10178en_US
dc.identifier.issn2045-2322-
dc.identifier.urihttps://www.nature.com/articles/s41598-018-28471-1-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/119421-
dc.description.abstractHydrocephalus is a common complication following subarachnoid haemorrhage (SAH) arising from spontaneous aneurysm rupture. The Hounsfield unit (HU) value from computed tomography scans may reflect bone mineral density, which correlates with body mass index, which in turn is related to postSAH ventricle size changes. We herein investigated potential associations between frontal skull HU values and ventricle size changes after SAH. HU values from four different areas in the frontal bone were averaged to minimize measurement errors. The bicaudate index and Evans ratio were measured using both baseline and follow-up CT images. CT images with bicaudate index >0.2 and Evans ratio > 0.3 simultaneously were defined as indicating ventriculomegaly. We included 232 consecutive patients with SAH due to primary spontaneous aneurysm rupture, who underwent clipping over almost a 9-year period at a single institution. The first tertile of frontal skull HU values in older patients (>= 55 years) was an independent predictor of ventriculomegaly after SAH, as compared to the third tertile in younger patients (hazard ratio, 4.01; 95% confidence interval 1.21-13.30; p = 0.023). The lower frontal skull HU value independently predicted ventricular enlargement post-SAH, due to the potential weak integrity of subarachnoid trabecular structures in younger patients.en_US
dc.language.isoen_USen_US
dc.publisherNATURE PUBLISHING GROUPen_US
dc.subjectBONE-MINERAL DENSITYen_US
dc.subjectGLOBAL CEREBRAL ATROPHYen_US
dc.subjectBODY-MASS INDEXen_US
dc.subjectCOLLAGEN TYPE-Ien_US
dc.subjectINTRACEREBRAL HEMORRHAGEen_US
dc.subjectOSTEOGENESIS IMPERFECTAen_US
dc.subjectCOMPUTED-TOMOGRAPHYen_US
dc.subjectHYDROCEPHALUSen_US
dc.subjectCTen_US
dc.subjectIMPACTen_US
dc.titleThe frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhageen_US
dc.typeArticleen_US
dc.relation.volume8-
dc.identifier.doi10.1038/s41598-018-28471-1-
dc.relation.page0-0-
dc.relation.journalSCIENTIFIC REPORTS-
dc.contributor.googleauthorWon, Yu Deok-
dc.contributor.googleauthorNa, Min Kyun-
dc.contributor.googleauthorKim, Choong Hyun-
dc.contributor.googleauthorKim, Jae Min-
dc.contributor.googleauthorCheong, Jin Hwan-
dc.contributor.googleauthorRyu, Je Il-
dc.contributor.googleauthorHan, Myung-Hoon-
dc.relation.code2018003596-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidgksmh80-
dc.identifier.orcidhttp://orcid.org/0000-0003-1728-5017-


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