Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jong Wook Hong | - |
dc.date.accessioned | 2019-12-08T09:24:10Z | - |
dc.date.available | 2019-12-08T09:24:10Z | - |
dc.date.issued | 2018-06 | - |
dc.identifier.citation | BIOCHIP JOURNAL, v. 12, no. 2, page. 123-127 | en_US |
dc.identifier.issn | 1976-0280 | - |
dc.identifier.issn | 2092-7843 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs13206-017-2210-z | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/119076 | - |
dc.description.abstract | Polydimethylsiloxane (PDMS) is commonly used in microchip fabrication due to its biocompatibility, which is essential for biological applications, as well as other properties, including transparency to visible light, controllable gas permeability, mechanical and heat stability, and elasticity. Despite these properties, adsorption of biomolecules remains a major limitation of PDMS in biochips. Methods to prevent sample adsorption have been reported, and herein we compare several surface engineering methods that do not incorporate plasma pretreatment. Three methods - Teflon coating, water-repellent spraying, and perfluorodecyltrichlorosilane (FDTS) blending - were compared by evaluating the amount of fluorescein-isothiocyanate- conjugated bovine serum albumin (FITC-BSA) adsorbed onto the biochips. FDTS-blended PDMS significantly inhibited protein adsorption and showed good oleophobicity, but provided the lowest visible light transmittance of all materials tested. | en_US |
dc.description.sponsorship | This research was supported by Global Frontier Project Grant (2014M3A6A4062860) and Small Grant Exploratory Research (NRF-2014R1A1A2A16055291) of the National Research Foundation funded by the Ministry of Science, ICT and Future Planning of Korea. The standard contact angle measurement following ISO 15989 and transmittance measurement were kindly supplied by Ceko, Inc. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | KOREAN BIOCHIP SOCIETY-KBCS | en_US |
dc.subject | PDMS | en_US |
dc.subject | Protein adsorption | en_US |
dc.subject | No plasma treatment | en_US |
dc.subject | Teflon | en_US |
dc.subject | Water-repellent | en_US |
dc.subject | Perfluorodecyltri-chlorosilane | en_US |
dc.subject | FDTS | en_US |
dc.subject | FITC-BSA | en_US |
dc.title | Comparison of Surface Modification Techniques on Polydimethylsiloxane to Prevent Protein Adsorption | en_US |
dc.type | Article | en_US |
dc.relation.no | 2 | - |
dc.relation.volume | 12 | - |
dc.identifier.doi | 10.1007/s13206-017-2210-z | - |
dc.relation.page | 123-127 | - |
dc.relation.journal | BIOCHIP JOURNAL | - |
dc.contributor.googleauthor | Shin, Soojeong | - |
dc.contributor.googleauthor | Kim, Nayeong | - |
dc.contributor.googleauthor | Hong, Jong Wook | - |
dc.relation.code | 2018004158 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | jwh | - |
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