Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정승준 | - |
dc.date.accessioned | 2019-12-07T20:51:58Z | - |
dc.date.available | 2019-12-07T20:51:58Z | - |
dc.date.issued | 2018-04 | - |
dc.identifier.citation | MOLECULAR NEUROBIOLOGY, v. 55, no. 4, page. 3513-3522 | en_US |
dc.identifier.issn | 0893-7648 | - |
dc.identifier.issn | 1559-1182 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs12035-017-0594-3 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/118462 | - |
dc.description.abstract | In an aging society with an increasing threat to higher brain cognitive functions due to dementia, it becomes imperative to identify new molecular remedies for supporting adult neurogenesis. Interleukin-6 (IL-6) is a promising cytokine that can support neurogenesis under conditions of neurodegeneration, and neuron replacement is eventually possible due to its agonistic acting soluble receptor sIL-6R. Here, we report that activation of the IL-6-signal transducer and activator of transcription 3 (STAT3) axis is neurogenic and has potential therapeutic applications for the treatment of neurodegenerative diseases such as Parkinson's disease (PD). | en_US |
dc.description.sponsorship | This study was supported by Hanyang University by providing a scholarship to Y.A.S. and by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2013R1A1A2009178). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | HUMANA PRESS INC | en_US |
dc.subject | BDNF | en_US |
dc.subject | Brain | en_US |
dc.subject | Interleukin-6 | en_US |
dc.subject | Neuron | en_US |
dc.subject | Neurotrophin | en_US |
dc.subject | STAT3 | en_US |
dc.title | Interleukin-6-Mediated Induced Pluripotent Stem Cell (iPSC)-Derived Neural Differentiation | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 55 | - |
dc.identifier.doi | 10.1007/s12035-017-0594-3 | - |
dc.relation.page | 3513-3522 | - |
dc.relation.journal | MOLECULAR NEUROBIOLOGY | - |
dc.contributor.googleauthor | Sulistio, Yanuar Alan | - |
dc.contributor.googleauthor | Lee, Han Kyu | - |
dc.contributor.googleauthor | Jung, Sung Jun | - |
dc.contributor.googleauthor | Heese, Klaus | - |
dc.relation.code | 2018000380 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | eurijj | - |
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