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dc.contributor.authorKUTZNER ARNE HOLGER-
dc.date.accessioned2019-12-04T05:50:16Z-
dc.date.available2019-12-04T05:50:16Z-
dc.date.issued2018-01-
dc.identifier.citationBIOLOGICAL CHEMISTRY, v. 399, no. 1, page. 55-61en_US
dc.identifier.issn1431-6730-
dc.identifier.issn1437-4315-
dc.identifier.urihttps://www.degruyter.com/view/j/bchm.2018.399.issue-1/hsz-2017-0190/hsz-2017-0190.xml-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/117229-
dc.description.abstractDue to an aging society with an increased dementia-induced threat to higher cognitive functions, it has become imperative to understand the molecular and cellular events controlling the memory and learning processes in the brain. Here, we suggest that the novel master gene pair |-SRGAP2-FAM72-| (SLIT-ROBO Rho GTPase activating the protein 2, family with sequence similarity to 72) reveals a new dogma for the regulation of neural stem cell (NSC) gene expression and is a distinctive player in the control of human brain plasticity. Insight into the specific regulation of the brain-specific neural master gene |-SRGAP2-FAM72-| may essentially contribute to novel therapeutic approaches to restore or improve higher cognitive functions.en_US
dc.description.sponsorshipThis study was supported by Hanyang University, which provided a scholarship to Ms. Nguyen Thi Thanh Ho, and by the Basic Science Research Program through the National Research Foundation of Korea (NRF), which was funded by the Ministry of Education (2015R1D1A1A01057243).en_US
dc.language.isoen_USen_US
dc.publisherWALTER DE GRUYTER GMBHen_US
dc.subjectbrainen_US
dc.subjectFAM72en_US
dc.subjectlearningen_US
dc.subjectmemoryen_US
dc.subjectneuronen_US
dc.subjectp17en_US
dc.subjectSRGAP2en_US
dc.subjectsynapseen_US
dc.titleBrain plasticity, cognitive functions and neural stem cells: a pivotal role for the brain-specific neural master geneen_US
dc.typeArticleen_US
dc.relation.no1-
dc.relation.volume399-
dc.identifier.doi10.1515/hsz-2017-0190-
dc.relation.page55-61-
dc.relation.journalJOURNAL OF BIOLOGICAL CHEMISTRY-
dc.contributor.googleauthorNguyen Thi Thanh Ho-
dc.contributor.googleauthorKutzner, Arne-
dc.contributor.googleauthorHeese, Klaus-
dc.relation.code2018001923-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDEPARTMENT OF INFORMATION SYSTEMS-
dc.identifier.pidkutzner-
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COLLEGE OF ENGINEERING[S](공과대학) > INFORMATION SYSTEMS(정보시스템학과) > Articles
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