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dc.contributor.author이원준-
dc.date.accessioned2019-12-03T06:47:25Z-
dc.date.available2019-12-03T06:47:25Z-
dc.date.issued2017-12-
dc.identifier.citationINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, v. 58, no. 14, page. 6449-6456en_US
dc.identifier.issn0146-0404-
dc.identifier.issn1552-5783-
dc.identifier.urihttps://iovs.arvojournals.org/article.aspx?articleid=2667224-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/116896-
dc.description.abstractPURPOSE. To evaluate the rate of change in ganglion cell-inner plexiform layer (GCIPL) thickness measured by optical coherence tomography (OCT) using a trend-based approach in early-stage glaucomatous eyes with disc hemorrhage (DH) and to compare the GCIPL thinning rate with that in glaucomatous eyes without DH.METHODS. This prospective observational study included 46 patients with early-stage open-angle glaucoma and DH who underwent serial spectral-domain OCT measurements for at least 30 months. The GCIPL thinning rate was determined in the global, superior, or inferior hemiretinas and in six macular sectors by linear regression and was compared between glaucomatous eyes with DH and fellow glaucomatous eyes without DH and between glaucomatous eyes with DH and non-DH glaucomatous control eyes.RESULTS. The GCIPL thinning rate (mean +/- standard deviation) was significantly more rapid in glaucomatous eyes with DH than in fellow eyes without DH in the inferior hemiretina (-1.07 +/- 0.75 vs. -0.44 +/- 0.54 mu m/y, P = 0.001), inferotemporal sector (-1.13 +/- 1.00 vs. -0.61 +/- 0.66 mu m/y, P = 0.028), and inferior sector (-1.33 +/- 0.79 vs. -0.42 +/- 0.78 mu m/y, P < 0.001). The GCIPL thinning rate was significantly more rapid in glaucomatous eyes with DH than in glaucomatous controls without DH in the global area (-0.78 +/- 0.85 vs. -0.32 +/- 0.48 mu m/y, P = 0.002), the inferior hemiretina (-1.00 +/- 0.94 vs. -0.37 +/- 0.67 mu m/y, P < 0.001), and the inferotemporal sector (-1.31 +/- 1.07 vs. -0.34 +/- 0.75 mu m/y, P < 0.001).CONCLUSIONS. The GCIPL thinning rate on OCT was significantly more rapid in glaucomatous eyes with DH than in fellow glaucomatous eyes without DH or glaucomatous control eyes without DH. DH could be associated with progression of glaucoma in terms of GCIPL thinning.en_US
dc.language.isoen_USen_US
dc.publisherASSOC RESEARCH VISION OPHTHALMOLOGY INCen_US
dc.subjectdisc hemorrhageen_US
dc.subjectganglion cell-inner plexiform layeren_US
dc.subjectoptical coherence tomographyen_US
dc.subjectglaucomaen_US
dc.subjecttrend-based analysisen_US
dc.titleEvaluation of Ganglion Cell-Inner Plexiform Layer Thinning in Eyes With Optic Disc Hemorrhage: A Trend-Based Progression Analysisen_US
dc.typeArticleen_US
dc.relation.no14-
dc.relation.volume58-
dc.identifier.doi10.1167/iovs.17-22547-
dc.relation.page6449-6456-
dc.relation.journalINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE-
dc.contributor.googleauthorLee, Won June-
dc.contributor.googleauthorKim, Young Kook-
dc.contributor.googleauthorPark, Ki Ho-
dc.contributor.googleauthorJeoung, Jin Wook-
dc.relation.code2017000102-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidwjoon0208-
dc.identifier.researcherIDY-8207-2018-
dc.identifier.orcidhttp://orcid.org/0000-0002-3506-7139-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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