Repository at Hanyang UniversityGRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S](의생명공학전문대학원)ETC
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dc.contributor.authorRamakrishna Suresh-
dc.date.accessioned2019-12-03T05:31:58Z-
dc.date.available2019-12-03T05:31:58Z-
dc.date.issued2017-12-
dc.identifier.citationDRUG DISCOVERY TODAY, v. 22, no. 12, page. 1816-1824en_US
dc.identifier.issn1359-6446-
dc.identifier.issn1878-5832-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1359644617300752?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/116843-
dc.description.abstractThe Ran-binding protein microtubule-organizing center (RanBPM) is a highly conserved nucleocytoplasmic protein involved in a variety of intracellular signaling pathways that control diverse cellular functions. RanBPM interacts with proteins that are linked to various diseases, including Alzheimer's disease (AD), schizophrenia (SCZ), and cancer. In this article, we define the characteristics of the scaffolding protein RanBPM and focus on its interaction partners in diverse physiological disorders, such as neurological diseases, fertility disorders, and cancer.en_US
dc.description.sponsorshipWe would like to thank all of Suri's laboratory members for their helpful discussion. This study was supported by a grant from the National Research Foundation of Korea (2015R1C1A1A01054482, 2015H1D3A1036065, 2015R1D1A1A01060907, 2017M3A9C6061361, 2017M3A9E4048172), and Medical Research Center (2017R1A5A2015395), funded by the National Research Foundation of Korea (NRF) of the Ministry of Science, ICT and Future Planning, Republic of Korea.en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCI LTDen_US
dc.subjectBINDING-PROTEIN RANBPMen_US
dc.subjectMICROTUBULE-ORGANIZING CENTERen_US
dc.subjectAMYLOID PRECURSOR PROTEINen_US
dc.subjectBETA PEPTIDE GENERATIONen_US
dc.subjectSCAFFOLDING PROTEINen_US
dc.subjectALZHEIMERS-DISEASEen_US
dc.subjectRANBP9-COFILIN PATHWAYen_US
dc.subjectINTERACTING PROTEINen_US
dc.subjectTUMOR-SUPPRESSORen_US
dc.subjectCELL-MIGRATIONen_US
dc.titleRanBPM: a potential therapeutic target for modulating diverse physiological disordersen_US
dc.typeArticleen_US
dc.relation.no12-
dc.relation.volume22-
dc.identifier.doi10.1016/j.drudis.2017.08.005-
dc.relation.page1816-1824-
dc.relation.journalDRUG DISCOVERY TODAY-
dc.contributor.googleauthorDas, Soumyadip-
dc.contributor.googleauthorSuresh, Bharathi-
dc.contributor.googleauthorKim, Hyongbum (Henry)-
dc.contributor.googleauthorRamakrishna, Suresh-
dc.relation.code2017000929-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S]-
dc.identifier.pidsuri28-
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