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RanBPM: a potential therapeutic target for modulating diverse physiological disorders
- Title
- RanBPM: a potential therapeutic target for modulating diverse physiological disorders
- Author
- Ramakrishna Suresh
- Keywords
- BINDING-PROTEIN RANBPM; MICROTUBULE-ORGANIZING CENTER; AMYLOID PRECURSOR PROTEIN; BETA PEPTIDE GENERATION; SCAFFOLDING PROTEIN; ALZHEIMERS-DISEASE; RANBP9-COFILIN PATHWAY; INTERACTING PROTEIN; TUMOR-SUPPRESSOR; CELL-MIGRATION
- Issue Date
- 2017-12
- Publisher
- ELSEVIER SCI LTD
- Citation
- DRUG DISCOVERY TODAY, v. 22, no. 12, page. 1816-1824
- Abstract
- The Ran-binding protein microtubule-organizing center (RanBPM) is a highly conserved nucleocytoplasmic protein involved in a variety of intracellular signaling pathways that control diverse cellular functions. RanBPM interacts with proteins that are linked to various diseases, including Alzheimer's disease (AD), schizophrenia (SCZ), and cancer. In this article, we define the characteristics of the scaffolding protein RanBPM and focus on its interaction partners in diverse physiological disorders, such as neurological diseases, fertility disorders, and cancer.
- URI
- https://www.sciencedirect.com/science/article/pii/S1359644617300752?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/116843
- ISSN
- 1359-6446; 1878-5832
- Appears in Collections:
- GRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S](의생명공학전문대학원) > ETC
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