132 0

RanBPM: a potential therapeutic target for modulating diverse physiological disorders

Title
RanBPM: a potential therapeutic target for modulating diverse physiological disorders
Author
Ramakrishna Suresh
Keywords
BINDING-PROTEIN RANBPM; MICROTUBULE-ORGANIZING CENTER; AMYLOID PRECURSOR PROTEIN; BETA PEPTIDE GENERATION; SCAFFOLDING PROTEIN; ALZHEIMERS-DISEASE; RANBP9-COFILIN PATHWAY; INTERACTING PROTEIN; TUMOR-SUPPRESSOR; CELL-MIGRATION
Issue Date
2017-12
Publisher
ELSEVIER SCI LTD
Citation
DRUG DISCOVERY TODAY, v. 22, no. 12, page. 1816-1824
Abstract
The Ran-binding protein microtubule-organizing center (RanBPM) is a highly conserved nucleocytoplasmic protein involved in a variety of intracellular signaling pathways that control diverse cellular functions. RanBPM interacts with proteins that are linked to various diseases, including Alzheimer's disease (AD), schizophrenia (SCZ), and cancer. In this article, we define the characteristics of the scaffolding protein RanBPM and focus on its interaction partners in diverse physiological disorders, such as neurological diseases, fertility disorders, and cancer.
URI
https://www.sciencedirect.com/science/article/pii/S1359644617300752?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/116843
ISSN
1359-6446; 1878-5832
DOI
10.1016/j.drudis.2017.08.005
Appears in Collections:
GRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S](의생명공학전문대학원) > ETC
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE