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Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review

Title
Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review
Author
한동운
Keywords
Pregnancy; Herbal medicines; Adverse effects; Safety; Asian countries
Issue Date
2017-11
Publisher
BMC
Citation
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, v. 17, Article no. 489
Abstract
Background: High prevalence of herbal medicines used in pregnancy and the lack of information on their safety is a public concern. Despite this, no significant research has been done regarding potential adverse effects of using herbal medicines during pregnancy, especially among developing Asian countries.Methods: Cross-sectional studies were searched up to year 2016 on PubMed/Medline and EMBASE, the data were extracted and quality of studies was assessed using the quality appraisal tool. The findings are reported in accordance to the PRISMA checklist (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). Classification on safety of identified herbal medicines was done based on current scientific literature.Results: This study included eight cross-sectional studies (2729 participants) from seven different Asian countries, of which 1283 (47.01%) women used one or more herbal medicines during pregnancy. Peppermint (22.8%), aniseed (14. 7%), olibanum (12.9%), flixweed seed (12.2%) and ginger (11.5%) were the most frequently used herbal medicines. Out of the 33 identified herbal medicines, 13 were classified as safe to use, five as use with caution, eight were potentially harmful to use in pregnancy and information on seven herbal medicines was not available in the current literature.Conclusions: Several herbal medicines identified in this review were classified to be potentially harmful or the information regarding safety in pregnancy was missing. It is recommended that contraindicated herbal medicines should be avoided and other herbals should be taken under supervision of a qualified health care practitioner. The classification regarding safety of herbal medicines in pregnancy can be utilized to create awareness on prevention of adverse effects.
URI
https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-017-1995-6https://repository.hanyang.ac.kr/handle/20.500.11754/116187
ISSN
1472-6882
DOI
10.1186/s12906-017-1995-6
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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