Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신용운 | - |
dc.date.accessioned | 2019-12-01T17:38:18Z | - |
dc.date.available | 2019-12-01T17:38:18Z | - |
dc.date.issued | 2017-10 | - |
dc.identifier.citation | BMC OPHTHALMOLOGY, v. 17, Article no. 182 | en_US |
dc.identifier.issn | 1471-2415 | - |
dc.identifier.uri | https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-017-0578-0 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/116039 | - |
dc.description.abstract | Background: To quantitatively compare short-term hard exudates (HEs) alteration in patients with diabetic macular edema (DME) after intravitreal triamcinolone, dexamethasone implant or bevacizumab injections. Methods: This retrospective study enrolled DME eyes with HEs that underwent a single-dose intravitreal injection of triamcinolone (25 eyes), dexamethasone implant (20 eyes), or three monthly injections of bevacizumab (25 eyes) and completed at least three months of follow-up. All patients were examined before and after 1, 2 and 3 months of injections. Using color fundus photographs, the amount of HEs was quantified by two masked graders. The difference in HEs area between baseline and each follow-up visit was compared among the three groups. Results: After three months, HEs area was reduced to 52.9 +/- 4.21% (P < 0.001) in the triamcinolone group, 63.6 +/- 6. 08% (P = 0.002) in the dexamethasone implant group, and 85.2 +/- 5.07% (P = 0.198) in the bevacizumab group. A significant reduction in HEs appeared at one month in the triamcinolone group (53.5 +/- 4.91%, P < 0.001) and at two months in the dexamethasone implant group (70.1 +/- 5.21%, P = 0.039). Conclusions: Our study suggests intravitreal steroids (triamcinolone, dexamethasone implants) significantly reduce HEs in DME patients on short-term follow-up, whereas intravitreal bevacizumab does not. Therefore, intravitreal steroids may be useful in DME with HEs in the fovea. | en_US |
dc.description.sponsorship | This work was supported by the research fund of National Research Foundation of Korea (NRF-2015R1C1A2A01053008). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | BMC | en_US |
dc.subject | Bevacizumab | en_US |
dc.subject | Dexamethasone implant | en_US |
dc.subject | Diabetic macular edema | en_US |
dc.subject | Hard exudate | en_US |
dc.subject | Triamcinolone | en_US |
dc.title | Quantitative evaluation of hard exudates in diabetic macular edema after short-term intravitreal triamcinolone, dexamethasone implant or bevacizumab injections | en_US |
dc.type | Article | en_US |
dc.relation.volume | 17 | - |
dc.identifier.doi | 10.1186/s12886-017-0578-0 | - |
dc.relation.page | 182-182 | - |
dc.relation.journal | BMC OPHTHALMOLOGY | - |
dc.contributor.googleauthor | Shin, Yong Un | - |
dc.contributor.googleauthor | Hong, Eun Hee | - |
dc.contributor.googleauthor | Lim, Han Woong | - |
dc.contributor.googleauthor | Kang, Min Ho | - |
dc.contributor.googleauthor | Seong, Mincheol | - |
dc.contributor.googleauthor | Cho, Heeyoon | - |
dc.relation.code | 2017004399 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | maculashin | - |
dc.identifier.researcherID | V-7668-2017 | - |
dc.identifier.orcid | http://orcid.org/0000-0003-1251-8985 | - |
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