Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyunsook Kim | - |
dc.date.accessioned | 2019-12-01T10:47:05Z | - |
dc.date.available | 2019-12-01T10:47:05Z | - |
dc.date.issued | 2017-10 | - |
dc.identifier.citation | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v. 65, no. 46, page. 10011-10019 | en_US |
dc.identifier.issn | 0021-8561 | - |
dc.identifier.issn | 1520-5118 | - |
dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acs.jafc.7b03764 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/115782 | - |
dc.description.abstract | Physiological properties of water-soluble exopolysaccharides (EPS) and residues after EPS removal (Res) from the probiotic kefir were determined in high-fat (HF) diet-fed CS7BL/6J mice. EPS solutions showed rheological properties and lower viscosity compared to those of,beta-glucan (BG). EPS significantly suppressed the adipogenesis of 3T3-L1 preadipocytes in a dose-dependent manner. Mice were fed HF diets containing 5% EPS, 5% BG, 8% Res, or 5% microcrystalline cellulose (control) for 4 weeks. Compared with the control, EPS supplementation significantly reduced HF diet-induced body weight gain, adipose tissue weight, and plasma very-low-density lipoprotein cholesterol concentration (P < 0.05). Res and BG significantly reduced body weight gain; however, reduction in adipose tissue weight was not statistically significant, suggesting that the antiobesity effect of EPS occurs due to viscosity and an additional factor. EPS supplementation significantly enhanced abundance of Akkermansia spp. in feces. These data indicate that EPS shows significant antiobesity effects possibly via intestinal microbiota alterations. | en_US |
dc.description.sponsorship | This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2015R1A2A2A01005017). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | AMER CHEMICAL SOC | en_US |
dc.subject | exopolysaccharides | en_US |
dc.subject | beta-glucan | en_US |
dc.subject | obesity | en_US |
dc.subject | Akkermansia | en_US |
dc.subject | intestinal microbiota | en_US |
dc.title | Antiobesity Effect of Exopolysaccharides Isolated from Kefir Grains | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1021/acs.jafc.7b03764 | - |
dc.relation.page | 10011-10019 | - |
dc.relation.journal | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
dc.contributor.googleauthor | Lim, Juha | - |
dc.contributor.googleauthor | Kale, Madhuvanti | - |
dc.contributor.googleauthor | Kim, Dong-Hyeon | - |
dc.contributor.googleauthor | Kim, Hong-Seok | - |
dc.contributor.googleauthor | Chon, Jung-Whan | - |
dc.contributor.googleauthor | Seo, Kun-Ho | - |
dc.contributor.googleauthor | Lee, Hyeon Gyu | - |
dc.contributor.googleauthor | Yokoyama, Wallace | - |
dc.contributor.googleauthor | Kim, Hyunsook | - |
dc.relation.code | 2017002069 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF HUMAN ECOLOGY[S] | - |
dc.sector.department | DEPARTMENT OF FOOD & NUTRITION | - |
dc.identifier.pid | hyunsk15 | - |
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