Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 고광웅 | - |
dc.date.accessioned | 2019-11-30T03:55:09Z | - |
dc.date.available | 2019-11-30T03:55:09Z | - |
dc.date.issued | 2017-08 | - |
dc.identifier.citation | LIPIDS, v. 52, no. 8, page. 665-673 | en_US |
dc.identifier.issn | 0024-4201 | - |
dc.identifier.issn | 1558-9307 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs00330-016-4662-2 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/115350 | - |
dc.description.abstract | Medium chain fatty acid (MCFA) escapes the formation of chylomicrons in the small intestine, resulting in energy expenditure through beta-oxidation. Diacylglycerol (DAG) is susceptible to oxidation rather than being stored in the adipose tissue. This study was conducted to verify the effect of MCE-DAG oil on body fat mass in vivo. Male C57BL/6 mice were randomly assigned to four groups (n = 12) as follows: (1) normal diet (18% kcal from fat), (2) canola oil as a control (40% kcal from canola oil), (3) MCE-DAG10 (10% kcal from MCE-DAG + 30% kcal from canola oil), and (4) MCE-DAG20 (20% kcal from MCE-DAG + 20% kcal from canola oil). The body weight and fat mass of MCE-DAG20 group mice were decreased relative to those of control mice (P < 0.05 and P < 0.001, respectively). Serum triacylglycerol (TAG) was decreased in both MCE-DAG10 and MCE-DAG20 groups (P < 0.01 and P < 0.05, respectively). Hormone sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) were increased in the MCE-DAG20 group relative to the control in white adipose tissue (WAT) (P < 0.05). Uncoupling protein 1 (UCP1) was also increased in the MCE-DAG20 group relative to the control in brown adipose tissue (BAT) (P < 0.05). In summary, MCE-DAG reduced body fat mass likely by stimulating lipolysis in WAT and thermogenesis in BAT. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | SPRINGER HEIDELBERG | en_US |
dc.subject | Medium-chain enriched diacylglycerol | en_US |
dc.subject | Body fat mass | en_US |
dc.subject | Lipolysis | en_US |
dc.subject | Thermogenesis | en_US |
dc.title | Medium-Chain Enriched Diacylglycerol (MCE-DAG) Oil Decreases Body Fat Mass in Mice by Increasing Lipolysis and Thermogenesis in Adipose Tissue | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 52 | - |
dc.identifier.doi | 10.1007/s11745-017-4277-7 | - |
dc.relation.page | 665-673 | - |
dc.relation.journal | LIPIDS | - |
dc.contributor.googleauthor | Kim, Haeun | - |
dc.contributor.googleauthor | Choe, Jee-Hwan | - |
dc.contributor.googleauthor | Choi, Jong Hun | - |
dc.contributor.googleauthor | Kim, Hun Jung | - |
dc.contributor.googleauthor | Park, Soo Hyun | - |
dc.contributor.googleauthor | Lee, Moon Won | - |
dc.contributor.googleauthor | Kim, Wooki | - |
dc.contributor.googleauthor | Go, Gwang-woong | - |
dc.relation.code | 2017001095 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF HUMAN ECOLOGY[S] | - |
dc.sector.department | DEPARTMENT OF FOOD & NUTRITION | - |
dc.identifier.pid | gwgo1015 | - |
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