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Biodegradation and metabolic fate of levofloxacin via a freshwater green alga, Scenedesmus obliquus in synthetic saline wastewater

Title
Biodegradation and metabolic fate of levofloxacin via a freshwater green alga, Scenedesmus obliquus in synthetic saline wastewater
Author
전병훈
Keywords
Levofloxacin; Scenedesmus obliquus; Saline wastewater; Bioremediation; Emerging contaminants
Issue Date
2017-07
Publisher
ELSEVIER SCIENCE BV
Citation
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, v. 25, page. 54-61
Abstract
Levofloxacin (LEV), a fluoroquinolone antibiotic has been frequently observed in water resources imposing ecotoxicological effects on aquatic microbiota. The biodegradation and metabolic fate of LEV via a microalga, Scenedesmus obliquus in synthetic saline wastewater were investigated in this study. LEV removal (1 mg L-1) by S. obliquus was relatively low in the synthetic wastewater without the addition of sodium chloride (NaCl); however, its removal increased significantly from 4.5 to 93.4% with increasing of its salinity from 0 to 171 mM NaCl. Kinetic studies showed that the removal rate constant (k) increased from 0.005 to 0.289 d(-1) and degradation half-life decreased from 272 to 5 d in the presence of NaCl (0-856 mM). The removal mechanism analysis showed that the major mechanism of NaCl mediated enhancement of LEV removal was the bioaccumulation and subsequent intracellular biodegradation of LEV in microalgal cells. Six metabolites were identified via gas chromatography-mass spectrometry analysis after biodegradation of LEV. A metabolic pathway was postulated with regard to various cellular biocatalytic reactions in S. obliquus, including decarboxylation, demethylation, dehydroxylation, side chain breakdown, and ring cleavage.
URI
https://www.sciencedirect.com/science/article/pii/S2211926416308414?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/114997
ISSN
2211-9264
DOI
10.1016/j.algal.2017.04.012
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > EARTH RESOURCES AND ENVIRONMENTAL ENGINEERING(자원환경공학과) > Articles
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