Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김희태 | - |
dc.date.accessioned | 2019-11-27T00:29:26Z | - |
dc.date.available | 2019-11-27T00:29:26Z | - |
dc.date.issued | 2017-07 | - |
dc.identifier.citation | JOURNAL OF CLINICAL ULTRASOUND, v. 45, no. 6, page. 337-342 | en_US |
dc.identifier.issn | 0091-2751 | - |
dc.identifier.issn | 1097-0096 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1002/jcu.22452 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/114900 | - |
dc.description.abstract | ObjectivesOrthostatic hypotension (OH) is controversially regarded as the cause of orthostatic dizziness in Parkinson's disease (PD). We sought to evaluate whether cerebral autoregulation is an alternative cause for orthostatic dizziness in PD patients, using transcranial Doppler monitoring during head-up tilting. MethodsForty-five PD patients with dizziness, 13 PD patients without dizziness, and 10 age-matched healthy controls were enrolled. Participants were divided into the following four groups: patients with dizziness and OH (group 1, n=22), patients with dizziness but no OH (n=23, group 2), patients without dizziness (n=11, group 3), and age-matched healthy controls (n=10, group 4). All participants underwent transcranial Doppler and blood pressure monitoring for 10 minutes during the head-up tilt test. Changes in the cerebral blood flow velocity (CBFV) in the middle cerebral artery and the mean blood pressure (mBP) within 3 minutes after head-up tilting were compared between groups. ResultsGroup 1 showed a significantly higher change in mBP (-16.310.8 mmHg) than groups 2 (-2.6 +/- 4.9), 3 (-2.2 +/- 3.6), or 4 (1.8 +/- 6.0) (p<0.001). However, groups 3 (4.6 +/- 3.0cm/s) and 4 (-4.2 +/- 2.5) showed a significantly smaller change in CBFV than groups 1 (-9.0 +/- 4.2) and 2 (-8.1 +/- 5.1) (p<0.01). ConclusionsOur results suggest that cerebral hypoperfusion contributes to dizziness in PD patients despite a lack of OH. Transcranial Doppler monitoring during head-up tilting may be a useful tool for evaluating dizziness in PD patients with or without OH. (c) 2016 Wiley Periodicals, Inc. J Clin Ultrasound45:337-342, 2017; | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY | en_US |
dc.subject | cerebral autoregulation | en_US |
dc.subject | orthostatic hypotension | en_US |
dc.subject | Parkinson's disease | en_US |
dc.title | Orthostatic dizziness in Parkinson's disease is attributed to cerebral hypoperfusion: A transcranial doppler study | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 45 | - |
dc.identifier.doi | 10.1002/jcu.22452 | - |
dc.relation.page | 337-342 | - |
dc.relation.journal | JOURNAL OF CLINICAL ULTRASOUND | - |
dc.contributor.googleauthor | Park, Jinse | - |
dc.contributor.googleauthor | Kim, Hee-Tae | - |
dc.contributor.googleauthor | Park, Kang Min | - |
dc.contributor.googleauthor | Ha, Sam Yeol | - |
dc.contributor.googleauthor | Kim, Sung Eun | - |
dc.contributor.googleauthor | Shin, Kyong Jin | - |
dc.contributor.googleauthor | Kim, Si Eun | - |
dc.contributor.googleauthor | Jang, Wooyoung | - |
dc.contributor.googleauthor | Kim, Ji Sun | - |
dc.contributor.googleauthor | Youn, Jinyoung | - |
dc.relation.code | 2017003624 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kimht | - |
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