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dc.contributor.author허란-
dc.date.accessioned2019-11-26T06:40:55Z-
dc.date.available2019-11-26T06:40:55Z-
dc.date.issued2017-06-
dc.identifier.citationINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, v. 33, no. 6, page. 927-935en_US
dc.identifier.issn1569-5794-
dc.identifier.issn1573-0743-
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs10554-017-1073-7-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/114695-
dc.description.abstractPurpose There are limited data regarding subclinical atherosclerosis in Middle Eastern countries. We aimed to describe and compare coronary computed tomographic angiography (CCTA) findings in Qatari native and South Asian migrants at increased risk of coronary artery disease (CAD).Methods We performed CCTA in 251 consecutive volunteers (126 South Asian, 125 Qatari, mean age 50.0 +/- 7.3 years, 27.1% female) at increased risk of cardiovascular disease. Given differences in baseline risk factors, we employed propensity score matching to create a cohort of 162 subjects for comparative analyses. We compared CAD severity, extent, plaque morphology, adverse plaque characteristics, and quantitative measures of atherosclerotic burden in both subgroups.Results After matching, no CAD was seen in 58.0% of South Asians and 49.4% of Qataris (p = 0.3), while obstructive CAD (>= 50% luminal stenosis) was present in 40.7% of South Asians and 49.4% of Qataris (p = 0.3). There was a high prevalence of adverse plaque characteristics in both ethnicities, particularly positive remodeling. South Asians had significantly smaller vessel and lumen volumes, but the percent aggregate plaque volumes were not significantly different (2.9 +/- 6.3% vs. 3.8 +/- 8.0%, p = 0.4).Conclusions In this first study of CCTA findings performed in a Middle Eastern country, we observed a high prevalence of obstructive CAD in a middle-aged cohort. There were no significant differences in CCTA findings between Qataris and South Asians after adjustment for clinical risk factors. Future studies are needed to identify patterns of coronary atherosclerosis by CCTA in non-European populations where cardiovascular disease is increasingly prevalent.en_US
dc.description.sponsorshipThis study was supported by the Qatar National Research Fund (NPRP 09-370-3-089) and in part, by a generous gift from the Dalio Institute of Cardiovascular Imaging (New York, NY, USA) and the Michael Wolk Foundation (New York, NY, USA). The funding agencies were not involved in the study design; collection, analysis, and interpretation of data; the writing of the report; or the decision to submit the article for publication.en_US
dc.language.isoen_USen_US
dc.publisherSPRINGERen_US
dc.subjectCoronary computed tomographic angiographyen_US
dc.subjectAtherosclerosisen_US
dc.subjectEthnicityen_US
dc.titleSubclinical atherosclerosis detected by coronary computed tomographic angiography in Qatar: a comparison between Qataris and south Asian migrants.en_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s10554-017-1073-7-
dc.relation.journalINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING-
dc.contributor.googleauthorSchulman-Marcus, Joshua-
dc.contributor.googleauthorHeo, Ran-
dc.contributor.googleauthorGransar, Heidi-
dc.contributor.googleauthorAl Suwaidi, Jassim-
dc.contributor.googleauthorAlkuwari, Maryam-
dc.contributor.googleauthorElmore, Kimberly-
dc.contributor.googleauthorGomez, Mille J.-
dc.contributor.googleauthorJayyousi, Amin-
dc.contributor.googleauthorZirie, Mahmoud-
dc.contributor.googleauthorMin, James K.-
dc.relation.code2017003606-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidcardiohr-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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