86 0

Subclinical atherosclerosis detected by coronary computed tomographic angiography in Qatar: a comparison between Qataris and south Asian migrants.

Title
Subclinical atherosclerosis detected by coronary computed tomographic angiography in Qatar: a comparison between Qataris and south Asian migrants.
Author
허란
Keywords
Coronary computed tomographic angiography; Atherosclerosis; Ethnicity
Issue Date
2017-06
Publisher
SPRINGER
Citation
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, v. 33, no. 6, page. 927-935
Abstract
Purpose There are limited data regarding subclinical atherosclerosis in Middle Eastern countries. We aimed to describe and compare coronary computed tomographic angiography (CCTA) findings in Qatari native and South Asian migrants at increased risk of coronary artery disease (CAD).Methods We performed CCTA in 251 consecutive volunteers (126 South Asian, 125 Qatari, mean age 50.0 +/- 7.3 years, 27.1% female) at increased risk of cardiovascular disease. Given differences in baseline risk factors, we employed propensity score matching to create a cohort of 162 subjects for comparative analyses. We compared CAD severity, extent, plaque morphology, adverse plaque characteristics, and quantitative measures of atherosclerotic burden in both subgroups.Results After matching, no CAD was seen in 58.0% of South Asians and 49.4% of Qataris (p = 0.3), while obstructive CAD (>= 50% luminal stenosis) was present in 40.7% of South Asians and 49.4% of Qataris (p = 0.3). There was a high prevalence of adverse plaque characteristics in both ethnicities, particularly positive remodeling. South Asians had significantly smaller vessel and lumen volumes, but the percent aggregate plaque volumes were not significantly different (2.9 +/- 6.3% vs. 3.8 +/- 8.0%, p = 0.4).Conclusions In this first study of CCTA findings performed in a Middle Eastern country, we observed a high prevalence of obstructive CAD in a middle-aged cohort. There were no significant differences in CCTA findings between Qataris and South Asians after adjustment for clinical risk factors. Future studies are needed to identify patterns of coronary atherosclerosis by CCTA in non-European populations where cardiovascular disease is increasingly prevalent.
URI
https://link.springer.com/article/10.1007%2Fs10554-017-1073-7https://repository.hanyang.ac.kr/handle/20.500.11754/114695
ISSN
1569-5794; 1573-0743
DOI
10.1007/s10554-017-1073-7
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE