96 0

Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department

Title
Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department
Author
고벽성
Keywords
qSOFA; Organ failure; Sepsis; Emergency department
Issue Date
2017-06
Publisher
W B SAUNDERS CO-ELSEVIER INC
Citation
JOURNAL OF CRITICAL CARE, v. 42, page. 12-17
Abstract
Purpose: It is unclear whether quick sequential (sepsis-related) organ failure assessment (qSOFA) also has prognostic value for organ failure in patients with a suspected infection. The aim of this study was to determine whether qSOFA has prognostic value when compared to systemic inflammatory response syndrome (SIRS) in predicting organ failure in patients with a suspected infection in an emergency department (ED). Methods: A retrospective observational study was conducted in an ED during a 9-year period. We analyzed the ability of qSOFA compared to SIRS to predict the development of organ failure in patients (defined as an increase in the SOFA score of 2 points or more) using the area under receiver operating characteristic (AUROC) curve. Results: A total of 1009 patients with suspected infection were finally included in the study. The predictive validity of qSOFA for organ failure was higher than that of SIRS (AUROC=0.814 vs. AUROC=0.662, p=0.02). qSOFA was also superior to SIRS in predicting in-hospital mortality (AUROC=0.733 vs. AUROC=0.599, p=0.04). When the qSOFA score was equal to or > 1, its sensitivity and specificity to predict organ failure was 75% and 82%, respectively. Conclusions: qSOFA has a superior ability compared to SIRS in predicting the occurrence of organ failure in patients with a suspected infection. However, given the low sensitivity of qSOFA, further confirmatory tests for organ failure are needed. (C) 2017 Elsevier Inc. All rights reserved.
URI
https://www.sciencedirect.com/science/article/abs/pii/S0883944117303957?via%3Dihubhttps://repository.hanyang.ac.kr/handle/20.500.11754/114691
ISSN
0883-9441; 1557-8615
DOI
10.1016/j.jcrc.2017.06.020
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE