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dc.contributor.author이종민-
dc.date.accessioned2019-11-26T05:21:18Z-
dc.date.available2019-11-26T05:21:18Z-
dc.date.issued2017-06-
dc.identifier.citationHUMAN BRAIN MAPPING, v. 38, no. 6, page. 2808-2818en_US
dc.identifier.issn1065-9471-
dc.identifier.issn1097-0193-
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/abs/10.1002/hbm.23570-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/114580-
dc.description.abstractBased on cytoarchitecture, the posterior cingulate cortex (PCC) is thought to be comprised of two distinct functional subregions: the dorsal and ventral PCC (dPCC and vPCC). However, functional subregions do not completely match anatomical boundaries in the human brain. To understand the relationship between the functional organization of regions and anatomical features, it is necessary to apply parcellation algorithms based on functional properties. We therefore defined functionally informed subregions in the human PCC by parcellation of regions with similar patterns of functional connectivity in the resting brain. We used various patterns of functional connectivity, namely local, whole-brain and diffuse functional connections of the PCC, and various clustering methods, namely hierarchical, spectral, and kmeans clustering to investigate the subregions of the PCC. Overall, the approximate anatomical boundaries and predicted functional regions were highly overlapped to each other. Using hierarchical clustering, the PCC could be clearly separated into two anatomical subregions, namely the dPCC and vPCC, and further divided into four subregions segregated by local functional connectivity patterns. We show that the PCC could be separated into two (dPCC and vPCC) or four subregions based on local functional connections and hierarchical clustering, and that subregions of PCC display differential global functional connectivity, particularly along the dorsal-ventral axis. These results suggest that differences in functional connectivity between dPCC and vPCC may be due to differences in local connectivity between these functionally hierarchical subregions of the PCC. (C) 2017 Wiley Periodicals, Inc.en_US
dc.description.sponsorshipContract grant sponsor: National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science, ICT & Future Planning); Contract grant number: 2016R1A2B3016609; Contract grant sponsor: Brain Research Program through the National Research Foundation of Korea (NRF) funded by the Korea government (Ministry of Science, ICT & Future Planning); Contract grant number: NRF-2014M3C7A1046050en_US
dc.language.isoen_USen_US
dc.publisherWILEYen_US
dc.subjectfunctional magnetic resonance imagingen_US
dc.subjectbrain connectivityen_US
dc.subjectresting stateen_US
dc.subjectclustering algorithmsen_US
dc.subjecthuman brainen_US
dc.titleFunctional Organization of the Human Posterior Cingulate Cortex, Revealed by Multiple Connectivity-Based Parcellation Methodsen_US
dc.typeArticleen_US
dc.relation.no6-
dc.relation.volume38-
dc.identifier.doi10.1002/hbm.23570-
dc.relation.page2808-2818-
dc.relation.journalHUMAN BRAIN MAPPING-
dc.contributor.googleauthorCha, Jungho-
dc.contributor.googleauthorJo, Hang Joon-
dc.contributor.googleauthorGibson, William S.-
dc.contributor.googleauthorLee, Jong-Min-
dc.relation.code2017001567-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDIVISION OF ELECTRICAL AND BIOMEDICAL ENGINEERING-
dc.identifier.pidljm-
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > ELECTRICAL AND BIOMEDICAL ENGINEERING(전기·생체공학부) > Articles
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