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dc.contributor.author윤영은-
dc.date.accessioned2019-11-26T04:24:44Z-
dc.date.available2019-11-26T04:24:44Z-
dc.date.issued2017-06-
dc.identifier.citationTRANSPLANTATION PROCEEDINGS, v. 49, no. 5, page. 930-934en_US
dc.identifier.issn0041-1345-
dc.identifier.issn1873-2623-
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S004113451730249X?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/114525-
dc.description.abstractBackground. Hyperuricemia has been associated with kidney disease and remains controversial with regard to its gender-specific differences and impact in living kidney donation.Methods. Between 2006 and 2015, charts of live kidney donors who underwent nephrectomy and had a minimum follow-up of 1 year were reviewed. A total of 291 donors were included and divided based on gender-specific pre-donation serum uric acid (SUA) tertiles. Renal functional outcomes included were estimated glomerular filtration rate (eGFR) at 6-month and 1-year follow-up and percentage of donors with a 1-year eGFR < 60 mL/min/1.72 m(2). Logistic regression analysis was done.Results. Mean SUA tertiles were 5.8 +/- 1.1 mg/dL in males and 4.1 +/- 1 mg/dL in females. Females in the highest tertile (SUA > 4.5 mg/dL) had lower 6-month (59.9 +/- 10.3 vs 66.9 +/- 14.1 vs 67.3 +/- 12.1; P = .018) and 1-year (60.8 +/- 10.6 vs 67.6 +/- 10.8 vs 67.8 +/- 11.8; P = .021) eGFR and a higher percentage of donors with 1-year eGFR < 60 mL/min/1.73 m(2) (59.5% vs 31.6% vs 23%; P = .002) compared with donors in the lower SUA tertiles (<= 4.5 mg/dL). In males, there were similar eGFRs among SUA tertiles at 6-month and 1-year follow-up. In multivariate analysis, SUA was shown to be a significant predictor of developing stage 3 CKD (eGFR < 60 mL/min/1.72 m(2)), 1 year after donation in females but not in males.Conclusions. Predonation SUA level is associated with the development of delayed renal recovery (GFR < 60 mL/min/1.72 m(2)) 1 year after donation in females but not in males.en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.subjectDISEASEen_US
dc.subjectHYPERURICEMIAen_US
dc.subjectASSOCIATIONen_US
dc.subjectPROGRESSIONen_US
dc.subjectMORTALITYen_US
dc.subjectSURVIVALen_US
dc.subjectTRANSPLANTATIONen_US
dc.titleInvestigating Serum Uric Acid as a Risk Factor in the Development of Delayed Renal Recovery in Living Kidney Donors.en_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.transproceed.2017.03.034-
dc.relation.journalTRANSPLANTATION PROCEEDINGS-
dc.contributor.googleauthorBravo, R. C.-
dc.contributor.googleauthorGamo, M. B.-
dc.contributor.googleauthorLee, H. H.-
dc.contributor.googleauthorYoon, Y. E.-
dc.contributor.googleauthorHan, W. K.-
dc.relation.code2017001147-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidurologistyoon-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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