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dc.contributor.author최성철-
dc.date.accessioned2019-11-26T01:05:18Z-
dc.date.available2019-11-26T01:05:18Z-
dc.date.issued2017-06-
dc.identifier.citationCERAMICS INTERNATIONAL, v. 43, no. 15, page. 12888-12892en_US
dc.identifier.issn0272-8842-
dc.identifier.issn1873-3956-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0272884217313986?via%3Dihub-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/114356-
dc.description.abstractPlasmid DNA was purified using core-shell gamma-Fe2O3@SiO2 nanoparticles synthesized by a common sol-gel method utilizing tetraethylorthosilicate (TEOS) as a silica precursor. The dispersibility and TEOS binding affinity of gamma-Fe2O3 nanoparticles were enhanced by acid/base treatment due to the formation of additional surface hydroxyl groups prior to SiO2 deposition. Since SiO2 was coated under basic conditions in the presence of ammonia as a catalyst, base-treated gamma-Fe2O3 nanoparticles were more suited for this modification due to exhibiting a larger zeta potential and a lower saturation magnetization loss. The performance of the synthesized gamma-Fe2O3@SiO2 nanoparticles with a 15-nm-thick SiO2 layer in the purification of plasmid DNA was compared to that of commercial Fe3O4-based magnetic beads. The used DNA samples exhibited similar purities, and all samples had similar theoretical plasmid DNA binding capacities. However, gamma-Fe2O3@SiO2 nanoparticles exhibited a faster separation speed and a larger saturation magnetization of 100 emu/g compared to that of commercial Fe3O4-based magnetic beads (75 emu/g).en_US
dc.description.sponsorshipThis work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (2014R1A2A1A11050220), Korea Institute of Energy Technology Evaluation and Planning (KETEP) grants (20142020103400) funded by the Korean Government Ministry of Trade, Industry, and Energy, and Technology Innovation Program (R0004801) funded by the Ministry of Trade, Industry & Energy (MI, Korea).en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCI LTDen_US
dc.subjectMaghemiteen_US
dc.subjectSurface treatmenten_US
dc.subjectCore-shell structureen_US
dc.subjectZeta potentialen_US
dc.subjectPlasmid DNA purificationen_US
dc.titlegamma-Fe2O3@SiO2 core-shell structured nanoparticle: Fabrication via surface treatment and application for plasmid DNA purificationen_US
dc.typeArticleen_US
dc.relation.no15-
dc.relation.volume43-
dc.identifier.doi10.1016/j.ceramint.2017.06.183-
dc.relation.page12888-12892-
dc.relation.journalCERAMICS INTERNATIONAL-
dc.contributor.googleauthorAn, Gye Seok-
dc.contributor.googleauthorChoi, Soo Wan-
dc.contributor.googleauthorChae, Dong Ho-
dc.contributor.googleauthorLee, Hyeon Seung-
dc.contributor.googleauthorKim, Hyeong-Jun-
dc.contributor.googleauthorKim, YooJin-
dc.contributor.googleauthorJun, Yeon-Gil-
dc.contributor.googleauthorChoi, Sung-Churl-
dc.relation.code2017001945-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDIVISION OF MATERIALS SCIENCE AND ENGINEERING-
dc.identifier.pidchoi0505-
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > MATERIALS SCIENCE AND ENGINEERING(신소재공학부) > Articles
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