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dc.contributor.author이현주-
dc.date.accessioned2019-11-25T05:15:55Z-
dc.date.available2019-11-25T05:15:55Z-
dc.date.issued2017-05-
dc.identifier.citationITALIAN JOURNAL OF PEDIATRICS, v. 43, Article no. 45en_US
dc.identifier.issn1720-8424-
dc.identifier.issn1824-7288-
dc.identifier.urihttps://ijponline.biomedcentral.com/articles/10.1186/s13052-017-0361-0-
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/114101-
dc.description.abstractBackground: To determine the efficacy and safety of early supplementation with 800 IU of vitamin D in very low birth weight (VLBW) infants. Methods: Sixty-six infants with a birth weight less than 1500 g admitted to the Neonatal Intensive Care Unit. Of these, 52 infants were eligible and received 800 IU/day vitamin D from 2 weeks of age. We examined 25-hydroxyvitamin-D (25[OH] D) levels from cord blood at birth and serum at 32 and 36 weeks of postmenstrual age. Results: The study infants were divided by cord-blood levels of 25(OH) D at birth into 25(OH) D concentrations < 10 ng/mL (n = 20) or >= 10 ng/mL (n = 29). Vitamin D intake of 800 IU/day safely achieved an 88% probability of vitamin D sufficiency at 36 weeks postmenstrual age in VLBW infants with cord-blood levels of 25(OH) D >= 10 ng/mL, and 65% probability of vitamin D sufficiency was observed in infants with 25 OHD concentrations < 10 ng/mL at birth. Conclusion: Considering the efficacy and safety of vitamin D supplementation in this study, vitamin D intake of 800 IU/day may enhance vitamin D status during early hospitalization in VLBW infants with 25 OHD concentrations < 10 ng/mL at birth. The clinical significance of optimal vitamin D intake in VLBW infants needs to be studied in larger controlled studies.en_US
dc.language.isoen_USen_US
dc.publisherBIOMED CENTRAL LTDen_US
dc.subjectVitamin Den_US
dc.subjectSupplementationen_US
dc.subjectPremature infantsen_US
dc.subjectFollow-upen_US
dc.subjectDXAen_US
dc.titleEfficacy and safety of early supplementation with 800 IU of vitamin D in very preterm infants followed by underlying levels of vitamin D at birthen_US
dc.typeArticleen_US
dc.relation.volume43-
dc.identifier.doi10.1186/s13052-017-0361-0-
dc.relation.page1-8-
dc.relation.journalITALIAN JOURNAL OF PEDIATRICS-
dc.contributor.googleauthorCho, Sang Yeun-
dc.contributor.googleauthorPark, Hyun-Kyung-
dc.contributor.googleauthorLee, Hyun Ju-
dc.relation.code2017011351-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidblesslee77-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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