Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 배상철 | - |
dc.date.accessioned | 2019-11-22T00:51:48Z | - |
dc.date.available | 2019-11-22T00:51:48Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.citation | CELLULAR AND MOLECULAR BIOLOGY, v. 63, no. 3, page. 29-35 | en_US |
dc.identifier.issn | 0145-5680 | - |
dc.identifier.issn | 1165-158X | - |
dc.identifier.uri | https://www.cellmolbiol.org/index.php/CMB/article/view/1414 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113382 | - |
dc.description.abstract | This study aimed to explore whether BANK1 polymorphisms are associated with susceptibility to autoimmune diseases. We conducted a meta-analysis on the associations between the BANK1 rs10516487, rs3733197, and rs17266594 polymorphisms and autoimmune diseases. Twenty-two articles with a total of 22,684 patients and 36,437 controls were included in the meta-analysis. Meta-analysis revealed a significant association between autoimmune diseases and the BANK1 rs10516487 T allele (OR = 1.161, 95% CI = 1.092-1.275, p = 1.9 x 10(-6), heterogeneity p < 0.001). The analysis also revealed an association between autoimmune diseases and the BANK1 rs3733197 A allele (OR = 1.178, 95% CI = 1.105-1.256, p = 4.5 x 10(-7), heterogeneity p = 0.002) and the rs17266594 T allele (OR = 1.189, 95% CI = 1.073-1.315, p = 0.001, heterogeneity p < 0.001). Meta-analysis by autoimmune disease type revealed an association between both systemic lupus erythematosus and systemic sclerosis and the BANK1 rs10516487 T allele (OR - 1.294, 95% CI - 1.232-1.360, p < 1.0 x 10(-8), heterogeneity p - 0.556; OR = 1.102, 95% CI = 1.027-1.183, p = 0.017, heterogeneity p = 0.048). However, meta-analysis failed to indicate an association between the BANK1 rs10516487 T allele and rheumatoid arthritis (RA; OR = 1.006, 95% CI = 1.956-1.058, p = 0.819). This meta-analysis demonstrates that BANK1 rs10516487, rs3733197, and rs17266594 polymorphisms are associated with susceptibility to autoimmune diseases. | en_US |
dc.description.sponsorship | This study was supported in part by a grant of the Korea Healthcare technology R& D Project, Ministry for Health and Welfare, Republic of Korea (HI15C2958). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | C M B ASSOC | en_US |
dc.subject | Autoimmune diseases | en_US |
dc.subject | BANK1 | en_US |
dc.subject | Polymorphism | en_US |
dc.subject | Meta-analysis | en_US |
dc.title | Association between BANK1 polymorphisms and susceptibility to autoimmune diseases: A meta-analysis | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 63 | - |
dc.identifier.doi | 10.14715/cmb/2017.63.3.6 | - |
dc.relation.page | 29-35 | - |
dc.relation.journal | CELLULAR AND MOLECULAR BIOLOGY | - |
dc.contributor.googleauthor | Bae, S-C. | - |
dc.contributor.googleauthor | Lee, Y. H. | - |
dc.relation.code | 2017001234 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | scbae | - |
dc.identifier.orcid | http://orcid.org/0000-0003-4658-1093 | - |
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