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Advancing host-directed therapy for tuberculosis: new therapeutic insights from the Toxoplasma gondii

Title
Advancing host-directed therapy for tuberculosis: new therapeutic insights from the Toxoplasma gondii
Author
양철수
Issue Date
2017-03
Publisher
SHARED SCIENCE PUBLISHERS OG
Citation
MICROBIAL CELL, v. 4, no. 3, page. 105-107
Abstract
Tuberculosis (TB) drug-development strategies, a wide range of candidate host-directed therapies (HDT) sincluding new and repurposed drugs, biologics, and cellular therapies-have been proposed to accelerate eradication of infection and overcome the problems associated with current treatment regimens. By investigating the interaction between macrophages and the intracellular parasite Toxoplasma gondii (T. gondii), we uncovered that infection-induced signaling pathways suggest possibilities for the development of novel therapeutic modalities for TB that target the intracellular signaling pathways permitting the replication of Mycobacterium tuberculosis (MTB).
URI
http://microbialcell.com/researcharticles/advancing-host-directed-therapy-for-tuberculosis-new-therapeutic-insights-from-the-toxoplasma-gondii/https://repository.hanyang.ac.kr/handle/20.500.11754/113354
ISSN
2311-2638
DOI
10.15698/mic2017.03.565
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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